DNA Regulatory Switch Helps Androgen Receptor Suppress Breast Cancer Cell Growth
Researchers have discovered a regulatory DNA enhancer switch inside the ZBTB16 gene that enables the androgen receptor to suppress cell ...
Tag: CRISPR
Gene Gains and Losses Shape Arthropod Evolution, Genomic Survey Finds
A new review argues that cheap, high-quality genome sequencing is revealing how gene gains, losses, duplications and horizontal transfers drive ...
Scientists Map How Genome Editing Could Arm Rice Against Drought, Salt and Heat
A new review outlines how CRISPR-based tools are being used to modify stress-responsive genes in rice and what still limits ...
Amplification Editing Duplicates Genomic Sequences from Base Pairs to Chromosomal Scale
A new genome-editing protocol called amplification editing uses paired prime-editing guides to duplicate genomic sequences ranging from tens of base ...
CRISPR cuts at wheat centromeres rewrite the karyotype in a single generation
Targeting CRISPR–Cas9 at centromeric retrotransposons in hexaploid bread wheat reconfigured up to 11 chromosomes in a single generation, yielding translocations, ...
AI-powered biosensors aim to speed antimicrobial resistance detection from clinic to global surveillance
A new review in Biomedical Microdevices examines how artificial intelligence integrated with microfluidic, electrochemical, optical and CRISPR-based biosensors could enable ...
Fungal biotechnology faces two valleys of death on the road from lab to factory
A new editorial argues that two valleys of death—strain engineering limits and complex regulation—still block fungal biotechnology from reaching industrial ...
Global Metagenomic Survey Maps CRISPR Spacers Across Earth’s Microbiomes
A planetary-scale mining of public metagenomes collected 794 million CRISPR spacers and 1.18 billion virus and plasmid hits, revealing high ...
Ultrasound and Light Guide Gene Editing to Selected Sites in Mouse Brains
A light-sensitive Cas12f editor and ultrasound-triggered nanoparticles enabled researchers to control gene disruption at a selected location in mouse brains.
Zebrafish Offer a Transparent Window Into Human Pigmentation Disorders
A new review details how transparent, genetically similar zebrafish enable real-time study of melanogenesis and human pigmentation disorders.
Africa’s GM Food Revolution Stalls at Just 15 of 54 Nations
A new review finds only 15 of Africa's 54 nations use GM crop technology, with misinformation, patchy regulations and missing ...
Zebrafish Study Points to tnni2a.3 as a Candidate Gene in Intermuscular Bone Formation
A spatial transcriptomic atlas of zebrafish muscle tissue identifies tnni2a.3 as a candidate gene associated with intermuscular bone formation, with ...
Fluorescent Reporter System Boosts Prime Editing Efficiency in Stem Cells
A new protocol details PINE-TREE, a transient fluorescent reporter system that enriches prime-edited human pluripotent stem cells and yields up ...
Viruses That Eat Bacteria Offer Livestock a Tool Against Antibiotic Resistance
A new review finds bacteriophage therapy shows promise against antibiotic-resistant livestock infections, but most evidence remains limited to laboratory and ...
CRISPR Antivirals Target Respiratory Viruses, but Lung Delivery Remains the Hurdle
A new review argues that CRISPR antivirals, especially RNA-targeting Cas13 systems, can suppress respiratory viruses in preclinical models, with lung ...
CRISPR-Edited Microalgae Boost Carotenoids but Hit Hard Limits on Carbon Capture
A new review finds CRISPR engineering can sharply raise carotenoid yields in microalgae, yet these gains mostly redistribute carbon rather ...
First Continuous Cell Lines End Six-Decade Quest to Culture Marine Invertebrate Cells
A new review chronicles six decades of marine invertebrate cell culture and the 2025 arrival of the first continuously proliferating ...
Engineered exosome nanocarriers emerge as targeted cardiovascular drug delivery platform
A new review outlines how engineered exosome nanocarriers could deliver drugs precisely to diseased heart tissue, while major manufacturing and ...
CAR-NK Cells Move From Concept Toward Clinic as Review Maps Engineering Fixes
A new review synthesizes engineering strategies and early clinical findings for CAR-NK cell immunotherapy in blood cancers and solid tumors.
CRISPR–Cas systems in Microcoleus cyanobacteria show a dynamic history of gene flow
A new study of 14 Microcoleus species finds that CRISPR–Cas systems are widespread but do not follow species phylogeny, pointing ...
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