Tag: ferroptosis

Liraglutide reduced proteinuria and kidney injury in lupus-prone mice through anti-inflammatory, antioxidant, and ferroptosis-related mechanisms, with cAMP signaling implicated.

Knocking down CISD2 suppresses gastric cancer cell growth and induces ferroptosis through inhibition of the mTOR/SREBF1/SCD1 axis and GPX4 downregulation, ...

A preclinical mouse study reports that the fungal-derived compound DM28 induces SLC3A2-linked ferroptosis and increases activated T cell infiltration when ...

A new narrative review synthesizes how the multifunctional protein JWA intersects with redox homeostasis across cancer, neurodegeneration and tissue injury, ...

A docetaxel-loaded iron copper sulfide nanoplatform combines chemotherapy, chemodynamic therapy and photothermal therapy to amplify ferroptosis in leukemia cells, according ...

A new study links macrophage STAT3 signaling to a paracrine inflammatory environment associated with ferroptosis-related cardiomyocyte injury in septic cardiomyopathy.

Nanoscale vesicle-like particles isolated from the medicinal herb Selaginella doederleinii suppressed liver cancer cells and tumors in mice by inducing ...

A Mendelian randomization study finds that ferroptosis-related genes influence acute myeloid leukemia risk directly and indirectly through specific immune cell ...

Researchers report Hi-APEX, a hydrogen peroxide-independent APEX2 labeling system that enabled protein and RNA proximity mapping in tumor xenografts and ...

In a rat model of contusive spinal cord injury, daily oral sodium selenite preserved oligodendrocytes and myelin and improved locomotor ...

A multi-cohort study finds that five genes upregulated in clear cell renal cell carcinoma mark the immune microenvironment rather than ...

Rabies virus matrix protein stabilizes RGS4 through incomplete autophagy, suppressing neuronal ferroptosis and supporting viral replication.

A narrative review links iron-dependent ferroptosis to tumor progression and therapy response in digestive system cancers, while flagging major barriers ...

A new mouse and cell study shows that inhibiting acid sphingomyelinase with desipramine lowers ceramide, curbs neuronal ferroptosis and reduces ...

A preclinical study reports that cardiomyocyte-targeted, ultrasound-responsive nanoparticles delivering Abelmoschus manihot extract suppressed radiation-induced ferroptosis and preserved heart function in ...

A preclinical study reports that Kangxianling Decoction reduced renal fibrosis in a rat model by suppressing ferroptosis through the p53/GPX4 ...

A new review summarizes how the amino acid transporter SLC7A5 drives tumor metabolic reprogramming and where targeted therapies against it ...

A new review finds edible source-derived exosome-like nanoparticles show preclinical promise against hepatocellular carcinoma, but clinical translation faces major hurdles.

A new preclinical study reports that artesunate suppresses activated synovial fibroblasts and eases collagen-induced arthritis in mice by inducing ferroptosis ...

A multi-omics study found that bacteriophage treatment reduced diarrhea in ETEC K88-infected weaned piglets while shifting gut bacteria, bile secretion, ...