Researchers have demonstrated that Astragalus polysaccharide protects oligodendrocytes and attenuates cuprizone-induced demyelination in mice through activation of the Nrf2 signaling ...
A review in Chinese Medicine evaluates preclinical evidence suggesting acupuncture may regulate mitochondrial homeostasis after traumatic brain injury, though direct ...
A single-center retrospective study indicates that a structured optic nerve protocol may facilitate delayed visual recovery following skull base tumor ...
A comprehensive review reveals that neurovascular unit dysfunction actively drives ischemic stroke progression and identifies multi-target strategies to improve recovery.
Repeated isoflurane exposure impaired memory and hippocampal CA1 function in mice, and pretreatment with the approved drug selegiline prevented most ...
A study in Fluids and Barriers of the CNS finds that the dual GLP-1/GIP agonist DA3-CH reduces oxidative stress and ...
A narrative review links mitochondrial breakdown, neuroinflammation, and endocrine stress responses within an integrative model of perinatal hypoxic-ischemic brain injury.
A new review finds that the traditional Chinese fruit Yi Zhi Ren shows broad neuroprotective and metabolic activity in cell ...
A new rat study reports that chitosan-coated selenium nanoparticles carrying Mucuna pruriens seed extract improved motor function, antioxidant levels, and ...
A systematic review and meta-analysis of nine studies reports moderate-certainty improvements in stroke scale scores with Cytoflavin, alongside high heterogeneity ...
A mouse study finds that age- and diet-dependent changes in astrocyte complexity within the hippocampal temporoammonic pathway parallel spatial learning ...
A new mouse study finds that the herbal compound astragaloside IV improved learning, memory, and synaptic structure after traumatic brain ...
A new mouse and cell study shows that inhibiting acid sphingomyelinase with desipramine lowers ceramide, curbs neuronal ferroptosis and reduces ...
A new review finds cannabidiol consistently reduces neuroinflammation and oxidative stress in Alzheimer's preclinical models, but evidence for amyloid, tau, ...
A narrative review finds that testosterone replacement therapy in Parkinson's disease shows context-dependent neuroprotective and neurotoxic effects in preclinical studies, ...
A mouse and cell-culture study finds that the RET protein in astrocytes helps protect nearby neurons from hemin-induced apoptosis after ...
A single intracerebroventricular dose of the ODN analog OP preserved tyrosine hydroxylase-positive neurons and reduced oxidative stress, inflammation, and miRNA ...
A new review examines how the α4β2 nicotinic receptor agonist varenicline might act on molecular pathways involved in neuropsychiatric disorders.
A new in vitro study finds that epicatechin gallate from green tea and genistin from soybeans inhibit cholinesterases, reduce oxidative ...
A study in Clinical and Experimental Medicine reports that TRIM11 protects microglia from oxidative stress and ferroptosis during cerebral ischemia ...
