Probiotics and children’s neurodevelopment research mapped in new bibliometric analysis
A bibliometric analysis of 1,684 Web of Science documents from 1998 to 2026 maps the rapid growth of probiotics and ...
Tag: Neuroinflammation
Neuron-derived CCL3 drives neuropathic pain after brachial plexus avulsion in mice
A mouse study finds that the chemokine CCL3, produced by neurons in the spinal dorsal horn, mediates neuropathic pain and ...
Parasite-Driven Brain Changes May Explain Epilepsy in Neurocysticercosis
A narrative mini-review argues that neurocysticercosis-related epilepsy arises from active parasite-host-neuron interactions, not inflammation alone.
Mouse Brain Study Uncovers NDN and IDE as Candidate Fragile X Biomarkers
RNA sequencing of fragile X model mice identified the proteins NDN and IDE as strongly upregulated candidate tissue biomarkers, with ...
Gut Microbes, Immune Signals and the Inflammatory Road to Parkinson’s Disease
A new review synthesizes evidence that gut microbial dysbiosis and immune dysregulation may fuel the neuroinflammation and neurodegeneration of Parkinson's ...
Losing cGAS Drives Microglial Decline and Progressive Neurodegeneration in Mice
A new mouse study finds that losing cGAS disrupts microglial homeostasis and drives progressive neurodegeneration from early adulthood.
Cannabidiol shows preclinical promise against Alzheimer’s disease, but key evidence gaps remain
A new review finds cannabidiol consistently reduces neuroinflammation and oxidative stress in Alzheimer's preclinical models, but evidence for amyloid, tau, ...
Psychobiotics and Fermented Foods May Target the Gut-Brain Axis in Alzheimer’s Disease
A new review finds that psychobiotics and fermented foods show neuroprotective effects in animal models of Alzheimer's disease, while clinical ...
Neural Stem Cells May Rewire the Immune Response After Spinal Cord Injury
A new review argues that neural stem cells may aid spinal cord injury recovery mainly by reprogramming macrophages and other ...
GPNMB–SMAD4 pathway links microglial inflammation to demyelination in diabetic cognitive dysfunction
A mouse and cell study finds that hyperglycemia lowers microglial GPNMB, disrupting its binding to SMAD4 and unleashing NF-κB-driven neuroinflammation ...
Testosterone Therapy Shows Mixed Effects in Parkinson’s Disease, Review Finds
A narrative review finds that testosterone replacement therapy in Parkinson's disease shows context-dependent neuroprotective and neurotoxic effects in preclinical studies, ...
Gut Microbiome Signals Track Alzheimer’s Disease, but Treatments Remain Experimental
A new review finds recurring gut microbiome signatures associated with Alzheimer's disease biomarkers, while most microbiome-targeted treatments remain experimental.
First Immune-Modulating Drug Trial Targets Neuroinflammation in Prodromal Parkinson’s Disease
A published protocol details the first randomised, placebo-controlled trial testing whether the oral drug PXS-4728A reduces PET-measured brain neuroinflammation in ...
Mitochondrial Cleanup and a DNA Sensor May Team Up to Drive Stroke Inflammation
A new review maps how mitophagy and the cGAS–STING pathway may jointly regulate post-stroke neuroinflammation through leaking mitochondrial DNA, based ...
Fetuin-A Reduction with Pioglitazone Eases Brain Inflammation in Aged Rats with Liver-Related Cognitive Impairment
In a rat study, lowering the protein Fetuin-A with pioglitazone was accompanied by reduced hippocampal neuroinflammation and recovered recognition memory ...
Psychobiotics and Polyphenols May Modulate the Gut-Brain Axis in Mental Health, Review Finds
A narrative review proposes that psychobiotics and polyphenols may support mental health care through microbiota-guided nutritional strategies, while noting limited ...
Circular RNA circSMOX Emerges as a Player in Muscle and Nerve Disease
A new mini review in Amino Acids summarizes what is known about the circular RNA circSMOX, which is upregulated in ...
Aerobic exercise eases depressive-like behavior in stressed mice by calming hippocampal inflammation
In mice exposed to chronic mild stress, aerobic exercise reduced depressive-like behaviors and hippocampal neuroinflammation by inhibiting the HMGB1/NF-κB pathway ...
Mitochondrial transfer emerges as a potential neurotherapeutic strategy for CNS disorders
A new review maps how intercellular mitochondrial transfer and transplantation could treat central nervous system disorders, while flagging dye-labeling artifacts ...
Magnesium Sulfate Shows Neuroprotective Effects in Mouse Model of Postoperative Cognitive Dysfunction
A new experimental study links magnesium sulfate's neuroprotective effects to AMPK/PINK1/Parkin signaling in postoperative cognitive dysfunction.
