Tag: mouse model

The experimental compound ISFP10, which selectively inhibits a fungal-specific cell wall enzyme, showed potent activity against Candida strains in vitro ...

Mice injected with bacterial endotoxin showed suppressed STAT1 signaling in splenocytes stimulated with interferon-gamma a day later, a new study ...

An organ-resolved proteomic study in mice maps shared and organ-specific host responses to disseminated Talaromyces marneffei infection.

Achyranthes bidentata lowered blood pressure and eased kidney injury in hypertensive mice while expanding the gut bacterium Dubosiella and remodeling ...

A mouse study shows that whether a first Schistosoma mansoni infection is single-sex or bisexual shapes pulmonary CD4+ memory T ...

A mouse study found that oral pretreatment with cinnamic acid at higher doses improved biochemical markers, modulated antioxidant and inflammatory ...

A four-week aerobic treadmill program in genetically diverse UM-HET3 mice produced distinct shifts in gut bacterial composition and a significantly ...

Researchers have created the first multi-omic atlas of the developing mouse thalamus, revealing that sensory and motor-associated neuronal lineages diverge ...

Long before a tooth bud becomes visible, an embryo must already decide where teeth will form. A new study in ...

A new dielectric barrier discharge device uses the wall of a sealed blood collection tube as its own plasma barrier, ...

New research identifies FGFR1 signaling as a critical factor in the survival of newly formed bone cells by organizing the ...

A mouse breast cancer study found that CD40-stimulated B cells recruited CD8+ T cells into tumors, influenced their organization and ...

A mouse study found that iron deficiency during pregnancy left persistent mineral and gene-expression changes in offspring brains despite normalization ...

A controlled study of mice with tau pathology found that BCG vaccination reduced brain inflammation and tau deposition and improved ...

New mouse research shows that type I interferon signaling restricts early Borrelia burgdorferi expansion by boosting macrophage uptake and killing, ...

A two-hour sciatic nerve constriction in mice triggered months of pain behaviors even after the nerve fully recovered, pointing to ...

A mouse study reports that benzo(a)pyrene exposure depletes ovarian follicles, damages uterine tissue, and expands ovarian cell populations marked by ...

Calycosin reduced myocardial injury in diabetic mice in association with increased Rab7a-dependent lipophagy, while Rab7a silencing removed its protective effects ...

Preclinical experiments found that erianin reduced prostate cancer cell activity and mouse tumor growth while lowering phosphorylation of the STAT3 ...

A nine-herb traditional Chinese formula reduced gut graft-vs.-host disease severity and suppressed FGF2/PI3K/Akt signaling in a mouse model, according to ...