Tag: mouse model

Single-cell transcriptomic analysis shows tree shrew sperm development resembles human and macaque patterns more closely than the mouse does.

A mouse study links maternal diabetes-induced cranial neural tube defects to elevated H3K18 crotonylation and silencing of AKT and PIKFYVE.

A mouse study finds that the chemokine CCL3, produced by neurons in the spinal dorsal horn, mediates neuropathic pain and ...

A new study reports that the flavonoid trilobatin reduced airway inflammation in a mouse model of asthma by suppressing NLRP3 ...

A new single-cell RNA sequencing study maps how topical imiquimod remodels splenic immune cells in a lupus-like mouse model, revealing ...

A mouse study finds that leukemia inhibitory factor alters the expression of several immune checkpoint-related genes in the decidua of ...

A mouse study finds that priming with an intramuscular mRNA vaccine before an intranasal adjuvanted booster, through a type I ...

A new mouse study shows that the RNA-binding protein hnRNPC supports cerebellar development by suppressing a cryptic exon in Mtf2 ...

A mouse study found that pairing wild-type Lactiplantibacillus plantarum C8 with an LPxTG-overexpressing engineered strain outperformed single strains in restoring ...

A new study links the palmitoyltransferase ZDHHC5 and its modification of NOD2 to neutrophil extracellular trap formation, mitophagy and lung ...

A new review argues that lactate released during aerobic exercise could modify the neuronal protein α-tubulin and support neural remodeling ...

An already approved cancer drug, dabrafenib, reduced and stabilised cerebral cavernous malformations in mouse models, supporting its repurposing as a ...

A bio-dissociable platinum quantum dot cluster nanozyme reduced endometriotic lesions and remodeled the inflammatory microenvironment in a mouse model, offering ...

A mouse study found that an asymmetric 0.16/0.18-mm BCAS configuration produced earlier cognitive impairment, more persistent sensorimotor deficits, and more ...

A mouse and cell-culture study finds that the RET protein in astrocytes helps protect nearby neurons from hemin-induced apoptosis after ...

In a mouse model of demyelination, OPCs shift toward an astrocyte-like state through opposing BMP and Wnt signaling, and blocking ...

Spray-dried microcapsules co-encapsulating lactic acid and ajwain essential oil showed antibacterial activity in vitro and partially attenuated infection-associated changes in ...

A mouse study finds that restoring parvalbumin signaling in the hippocampus rescues epilepsy-related cognitive impairment by regulating CaMKIIα autophosphorylation and ...

Plant-derived silver nanoparticles embedded in injectable thermosensitive chitosan hydrogels achieved near-complete burn wound closure in mice by day 21.

Researchers have developed a protocol that keeps mouse bone and marrow alive in a dish for up to four weeks ...