Tag: BDNF

A new review in Molecular Biology Reports synthesizes in vitro, animal, and clinical evidence on six molecular mechanisms by which ...

In a CRISPR rat model of Parkinson's disease, replenishing BDNF unexpectedly exacerbated graft-induced dyskinesia through mechanisms involving an immature phenotype ...

A single session of vagus nerve stimulation improved memory and hippocampal plasticity in female rats, but only when tested during ...

A rat study links a two-week PKCα surge in the perirhinal cortex to dendritic growth that precedes memory gains in ...

A new narrative review synthesizes evidence that moderate-intensity aerobic exercise optimally activates the BDNF/PI3K/Akt neurorepair pathway after ischemic stroke, while ...

A narrative review synthesizes evidence that task-oriented circuit training improves walking endurance, gait speed and balance after stroke, and may ...

A rat study found that 14 days of REM sleep deprivation produced manic- and OCD-like behaviors in both sexes and ...

A new mouse study shows the liver-derived hormone FGF21 crosses the blood-brain barrier through a saturable, efflux-limited transport system and ...

A new review finds that psychobiotics and fermented foods show neuroprotective effects in animal models of Alzheimer's disease, while clinical ...

A rat study finds that treadmill exercise, especially at moderate intensity, partially restores memory and brain BDNF levels during morphine ...

Co-culturing human brain endothelial cells with pericytes activates AKT and ERK insulin signaling, raises TIMP1 and collagen-IV, inhibits MMP activity ...

A 14-day study in male rats found that an ethanolic extract of Achillea fragrantissima reduced locomotor activity and grip strength ...

A lion's mane mushroom polysaccharide partially reversed metabolic, intestinal barrier, and spatial memory deficits in mice fed a high-fat, high-sucrose ...

A randomized trial in GeroScience reports that a single bout of blood flow restriction training acutely increased circulating BDNF and ...

In a cross-sectional study of 240 patients with chronic kidney disease, higher serum BDNF levels and a BDNF-to-kidney-function ratio were ...

A rat study found that post-weaning DHA or EPA diets reduced forced-swim immobility and partially restored prefrontal-cortex myelin measures in ...

An eight-week study of 40 male Wistar rats found that hippocampal BDNF responses and cognitive performance varied across endurance, rotarod, ...

A new review argues that the optically transparent zebrafish offers a uniquely powerful translational model for decoding how obesity dismantles ...

A sweeping integrative review argues that major depressive disorder arises from interacting molecular dysregulation and large-scale brain network dysfunction, while ...

A 12-week trial found that high-intensity interval training, but not moderate continuous exercise, significantly raised resting plasma BDNF and improved ...