Commentary Questions Anorexia Nervosa Diagnostic Shift
A commentary in the Journal of Eating Disorders argues that shifting anorexia nervosa diagnosis from observable signs to psychological symptoms ...
Tag: animal models
Electroacupuncture Linked to Reduced Heart Injury in Animal Models
A systematic review and meta-analysis finds that electroacupuncture preconditioning is associated with reduced myocardial injury and favorable mitochondria-associated changes in ...
Multiregional Brain Sensing Predicts Parkinson’s Motor Fluctuations in Animal Models
A multiregional neural sensing framework using machine learning predicted Parkinson's disease motor fluctuations with nearly ninety percent accuracy across animal ...
Slug-inspired injectable hydrogel seals gastrointestinal fistulas in rats and pigs
An injectable, slug-inspired hydrogel with single-step Janus-type tissue adhesion repaired gastrointestinal fistulas in rats and miniature pigs via endoscopic delivery.
Mouse models anchor Chandipura virus research as vaccine and drug candidates advance
A new review finds that neonatal and juvenile mice have carried nearly all Chandipura virus model research, supporting preclinical vaccine ...
Body Fat May Set the Stage for Lymphedema, Researchers Propose
A new hypothesis paper proposes that the volume of subcutaneous fat present before lymphatic injury may determine whether lymphedema develops ...
Experimental Feline Calicivirus Vaccine Strain WH24 Shows Broad Protection in Cats
A Chinese study identified the feline calicivirus strain WH24 as a vaccine candidate that protected cats against challenge with both ...
Witnessing Defeat Is Not the Same as Suffering It: Mouse Study Shows Two Stress Models Diverge
A controlled mouse study finds that witnessed social defeat produces overlapping but distinct behavioral and hippocampal molecular effects from direct ...
AI Unifies Cell Types Across 700 Million Years
The AI system Unify connected 125 cell types across seven species spanning more than 700 million years by comparing gene ...
Review maps polystyrene nanoplastic reproductive risks in experimental models
A review of 114 studies associates polystyrene nanoplastics with reproductive and developmental effects in experimental models but emphasizes that human ...
Rotenone-induced Parkinsonism in mice reverses within a year
A 12-month longitudinal study finds that Parkinson-like motor deficits and dopaminergic pathology caused by chronic rotenone exposure in mice fully ...
ACSS2 inhibition boosts cabozantinib activity in liver cancer models
Preclinical hepatocellular carcinoma models showed that blocking ACSS2 or autophagy enhanced cabozantinib’s antitumor activity by disrupting a TFEB-linked protective response.
Editorial reviews clinical, epidemiological and preclinical evidence on alcohol use disorder targets
A 2026 editorial synthesizes epidemiological, clinical and preclinical evidence highlighting candidate pharmacological targets for alcohol use disorder while emphasizing that ...
Preclinical Review Links Natural Compounds to PPARγ in Colitis Models
A 2026 review finds that several natural compounds alter PPARγ-related pathways in cellular and mouse models of ulcerative colitis, but ...
Smart nanoplatforms aim to make sepsis therapy responsive to disease stage
A review finds that stimulus-responsive nanoparticles can detect pathological signals in sepsis models and release antimicrobial, anti-inflammatory and immune-regulating drugs ...
Theobromine Shows Parkinson’s Promise, but Human Evidence Remains Thin
Biochemical and animal studies suggest that cocoa-derived theobromine can affect monoamine oxidase, adenosine and neuronal signaling, but no clinical evidence ...
Systematic review maps ellagic acid’s bone effects in preclinical models
A systematic review of 13 cell and animal studies reports bone-protective effects of ellagic acid in preclinical osteoporosis models, but ...
Inside the UC Davis Testing Center Putting Lab-Grown Organoids and AI Models to the Real-World Test
The UC Davis NAMs Testing Center offers an independent, fit-for-purpose evaluation model for organoids, microphysiological systems and computational tools as ...
How Metabolic Syndrome Rewires the Bladder: Animal Models Reveal Key Mechanisms
A new review in Nature Reviews Urology synthesizes how animal models of diabetes, obesity, dyslipidaemia and hypertension reveal the mechanisms ...
Scientists Propose Framework to Test Whether Oropouche Virus Harms Fetuses
Researchers propose a combined experimental and epidemiological framework to determine whether Oropouche virus can cause vertical transmission and adverse fetal ...
