Biology

A computationally designed multi-epitope subunit vaccine called FLPD protected 65 percent of mice and 70 percent of chickens against lethal...

FloA drives internalization of the PmaA proton pump during calcium stress, protecting fungal cells from calcium overload.

A pilot study at a Swedish research centre found that gestating sows markedly shifted their use of resting areas toward...

An updated meta-analysis of 18 randomized controlled trials finds synbiotic supplementation associated with favorable shifts in several oxidative stress biomarkers,...

A four-generation experiment with wild house mice in island-like enclosures finds rapid plastic shifts in body mass, vertebrae length and...

RNA sequencing of 18 canine brain tumors reveals 45 genes expressed at different levels in French bulldogs compared with boxers...

New cell and tissue research finds that the inflammatory cytokine IL-8 drives epithelial-mesenchymal transition and invasiveness in COPD-associated lung cancer...

A new review argues that stem cell grafts can protect tissue and communicate with host circuits in selected spinal cord...

Deleting Trpv1 in myeloid cells worsened inflammation, fibrosis and barrier dysfunction in mice with high-fat diet-exacerbated chronic colitis, via a...

Methanol extracts of lesser chickweed from Egypt showed the strongest phenolic content, antioxidant scavenging, and antimicrobial activity in new laboratory...

Single-cell and spatial profiling of pancreatic tumors reveals a reinforcing loop between mature dendritic cells and regulatory T cells, mediated...

Researchers report a convenient synthesis of carboxypolyamine substrates and hydroxylamine-containing analogs designed to selectively inhibit carboxyspermidine decarboxylase in bacterial polyamine...

Deleting the Myc gene in mouse granulosa cells disrupts glycerophospholipid metabolism, damages oocyte spindles and causes female infertility.

Deleting the epigenetic regulator Ash2l from developing palatal mesenchyme collapses the H3K4me3 histone mark, silences Wnt5b, and produces complete cleft...

Researchers developed a 30-meter fuel model classification for the Czech Republic, revealing that existing coarse European fuel maps substantially understate...

A four-gene transcriptomic signature stratifies prostate cancer patients by biochemical recurrence risk and identifies SPAG5 as a targetable oncogene.

A new review details how the ICH M7 guideline assesses and controls mutagenic impurities in pharmaceuticals, from the Ames test...

Laboratory testing shows cuminaldehyde guanylhydrazone, thymol and ethyl lauroyl arginate kill dairy pathogens within minutes, even in manure, milk and...

Using multi-parent crosses and marker-assisted selection, rice breeders have developed lines carrying up to seven resistance genes against blast, bacterial...

A five-year retrospective cohort study found neonatal FVRCP vaccination in shelter kittens was associated with lower 90-day mortality and no...