Genes and metabolites behind why some foxtail millet grains taste better
A multi-omics study of 12 foxtail millet varieties links flavonoid, anthocyanin and terpenoid pathways with reduced bitter metabolites to better ...
Tag: Transcriptomics
Chlorpyrifos Exposure Linked to Autism-Associated Genes in Computational Study
A computational study identified 206 shared genes and an exploratory four-gene signature linking chlorpyrifos targets to autism-associated pathways.
Gut Microbiota Imbalance Tied to Larval Health in Black Soldier Fly Pig Manure Recycling
A multi-omics study of one black soldier fly rearing event linked gut bacterial and fungal dysbiosis to larval health divergence ...
Multi-omics study maps how crossbreeding shapes fat and flavor in rabbit meat
A multi-omics study of reciprocal crossbred rabbits identified genes, metabolites and volatile compounds linked to intramuscular fat and meat flavor.
Three Oxidative Stress Genes Emerged as Key Players in Kidney Reperfusion Injury
A combined bioinformatic and experimental study identified FOS, FOSB and GDF15 as oxidative stress-related genes upregulated in renal ischemia-reperfusion injury ...
Tick Study Points to Mineral Absorption in Cinnamaldehyde Stress Response
Multi-omics analysis of Haemaphysalis longicornis exposed to cinnamaldehyde identifies mineral absorption as a candidate pathway in the tick's stress response.
Research report: Carnosine enhances mouse oocyte vitrification outcomes with associated redox and transcriptional changes
A mouse study found that adding carnosine during oocyte vitrification improved blastocyst formation rates and was associated with reduced oxidative ...
Glucose Boosts Fish Pathogen Fitness While Silencing a Key Virulence Weapon
A laboratory study found that glucose enhances growth, adhesion and biofilm formation in Pseudomonas plecoglossicida while transcriptionally repressing the T6SS ...
Progenitor cells dominate antiviral gene responses to Zika in fetal neural tissue
A secondary analysis of single-cell data finds that progenitor-enriched radial glia-like cells and cycling neural progenitor cells show the strongest ...
Genetic study links gut microbes to ulcerative colitis and flags two biomarkers
A Mendelian randomization and transcriptomic study identified 11 gut microbial taxa genetically associated with ulcerative colitis and nominated PHLPP2 and ...
PFAS replacement GenX triggers apoptosis and oxidative stress in prostate stromal cells at nanomolar doses
A new study reports that nanomolar GenX exposure reduces viability, triggers caspase-3- and PARP-associated apoptosis, raises ROS, and remodels 218 ...
Rumen bacterium and methanogens reshuffle metabolism to share hydrogen
A laboratory study of Ruminococcus albus 7 with four Methanobrevibacter strains reveals partner-specific shifts in hydrogen metabolism, biofilm genes and ...
Rat study maps gene and protein shifts in brown fat during cold acclimatization
A combined transcriptomic and proteomic analysis of brown adipose tissue in cold-exposed rats identified thousands of gene and protein expression ...
Blood Gene Study Nominally Flags SLC51A and TPMT as Aneurysm Markers
An integrative analysis of blood transcriptomics and genetic data nominally prioritizes SLC51A and TPMT as exploratory candidate diagnostic genes for ...
Synonymous mutations show no consistent prognostic role across cancers
A pan-cancer analysis of 8136 TCGA patients found no consistent survival association for functionally prioritized synonymous mutations, though selected cancer-specific ...
Antarctic Pond Bacterium Survives Calcium Levels Once Thought Fatal to Life
A bacterium isolated from ephemeral microbial mats at Antarctica's Don Juan Pond survived three months in 3.0 molar calcium chloride ...
Melatonin eases drought injury in maize seedlings, with effects differing by dose
A seven-day experiment in maize seedlings found that 50 and 100 micromoles per litre of melatonin partially alleviated drought injury ...
FOXO1 Emerges as Candidate Regulator and Biomarker in Hip Dysplasia
A study links the transcription factor FOXO1 to chondrocyte proliferation, apoptosis and disease severity in developmental dysplasia of the hip.
Research report: Bio-dissociable platinum quantum dot cluster nanozymes for nonhormonal endometriosis therapy through microenvironment remodeling
A bio-dissociable platinum quantum dot cluster nanozyme reduced endometriotic lesions and remodeled the inflammatory microenvironment in a mouse model, offering ...
Fungal Hormone Hypothesis Gains Ground as Heptelidic Acid Loss Silences Metabolite Genes in Trichoderma virens
Deleting the heptelidic acid synthase gene in Trichoderma virens silenced hundreds of secondary metabolism genes and erased the fungus's major ...
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