Molecular tools and consumer taste converge to reshape semi-arid tomato breeding
A new review synthesises how genetic diversity, molecular markers, genome editing and consumer sensory preferences can be integrated to breed ...
Tag: Transcriptomics
Exercise-linked gene Ticam2 emerges as candidate ALS drug target in mice
A new mouse study links exercise-induced gene-expression changes to the microglial gene Ticam2, which shows potential as a therapeutic target ...
Engineered nanoparticles disrupt chloroplasts, cutting photosynthesis and plant growth
A review of 239 studies finds that engineered nanoparticles disrupt Photosystem II, pigment content and RuBisCO activity, with downstream losses ...
Microalgae Turn Antibiotic Pollution Into Biofuel Feedstock Even in the Cold
A new study finds that cold-stressed microalgae remove over 90 percent of tetracycline from water while accumulating lipids at up ...
Fungal protein FpSmi1 shapes growth, virulence and fungicide response in wheat pathogen
Deleting the FpSmi1 gene in Fusarium pseudograminearum impairs fungal growth, spore formation and virulence while altering triazole fungicide sensitivity.
Single-cell study links an eight-gene program to LSC17-high acute myeloid leukemia
An integrative single-cell and bulk transcriptomic analysis identified an eight-gene non-LSC17 companion program associated with LSC17-high acute myeloid leukemia and ...
Gene Expression Differences in Canine Brain Tumours Revealed by Breed Comparisons
An analysis of RNA from high grade oligodendroglioma tissue found 31 genes differentially expressed between French Bulldogs and closely related ...
Maternal BMI Leaves Distinct Molecular Fingerprints in Placenta, Mother and Fetus
An exploratory multi-compartment study found that higher third-trimester maternal BMI is associated with distinct gene-expression and pathway signatures in maternal ...
SAT1 Overexpression Eases Alpha-Synuclein Toxicity in Fly Model of Parkinson’s Disease
In a Drosophila model of Parkinson's disease, neuronal overexpression of the polyamine enzyme SAT1 reduced alpha-synuclein protein levels, modified stress-response ...
Coppicing Switches On Isoflavonoid Genes in Three-Flowered Maple Regeneration
A multi-omics study of three-flowered maple links coppicing to activation of the isoflavonoid biosynthesis pathway and correlated regenerative traits.
Bacterial synthetic communities reshape how sugarcane responds to drought stress
A transcriptomic study finds that a five-member bacterial synthetic community alters sugarcane gene expression under drought, shifting signaling from hormone-based ...
Springtail Hox Protein Reveals Evolutionary Middle Ground in Losing Abdominal Limbs
A study of the springtail Folsomia candida shows that its Ubx protein binds and represses the appendage gene Dll like ...
From Association to Cause: Review Maps Causal Inference Methods for Alzheimer’s Molecular Data
A new review surveys causal-inference methods applied to Alzheimer's molecular data, finding that many observational associations lack genetic support and ...
Research report: Comparative transcriptomics reveals genotype-specific mechanisms of saline-alkali tolerance in highland barley
A comparative transcriptomic study finds that tolerant highland barley genotype L86 shows broader transcriptional activation of antioxidant, metabolic, and regulatory ...
Three lung inflammation sub-phenotypes in pneumonia may reshape critical care treatment
Transcriptomic analysis of lung cells from patients with severe pneumonia has revealed three distinct pulmonary sub-phenotypes that cannot be detected ...
Two Gene Biomarkers Linked to Sperm Production Failure in Infertility Study
An integrative analysis of human NOA transcriptomic data and a Utf1 conditional knockout mouse model identifies ACTRT2 and AKAP4 as ...
Dodecaploid Desert Shrub Genome Reveals Polyploidy-Driven Arid Adaptation
A telomere-to-telomere genome assembly of the dodecaploid desert shrub Prunus pedunculata reveals an autopolyploid origin and duplicated genes repurposed for ...
Tree Shrews Mirror Human Sperm Development Better Than Mice, Study Finds
Single-cell transcriptomic analysis shows tree shrew sperm development resembles human and macaque patterns more closely than the mouse does.
Knocking out three transporters reshapes selenium metabolism in engineered Bacillus subtilis
Researchers identified three Bacillus subtilis transporters that move Se-methylselenocysteine into cells and found that deleting their genes triggers selenomethionine formation ...
Lab-Grown Tumors From Dogs’ Noses Open a New Window on Hard-to-Treat Cancer
Japanese researchers have established the first patient-derived organoid model of canine nasal carcinoma, showing variable drug sensitivities among tumor lines ...
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