Tag: Immune checkpoint inhibitors

A new review finds checkpoint inhibitors are safe and effective for virologically suppressed people with HIV, while sub-Saharan Africa remains ...

A new review examines how patient-derived tumor organoids retaining immune cells could improve preclinical prediction of immunotherapy response while noting ...

A new review details how engineered oncolytic viruses selectively kill tumors, ignite antitumor immunity, and where clinical translation still falls ...

A new review finds that combining immune-checkpoint inhibitors with locoregional therapies improves progression-free survival in hepatocellular carcinoma, but overall survival ...

A new study reports that the RNA m5C methyltransferase NSUN2 suppresses CCL5-driven CD8+ T cell recruitment in lung adenocarcinoma through ...

Organoid and clinical single-cell data link a DHX58-positive, CD62L-positive stem-like T-cell state to immune checkpoint blockade responsiveness in gastric cancer.

A systematic review proposes a clinically actionable biomarker stratification for immunotherapy in microsatellite-stable colorectal cancer, where response rates to checkpoint ...

A multi-phase Nature Cancer study found that an agentic AI system detected immune-related adverse events in clinical notes with retrospective ...

A retrospective bicentric study of 158 metastatic melanoma patients found that CT radiomics offered no conclusive improvement over simple tumor ...

A new review examines how chemotherapeutic agents damage sperm DNA and germ cells, and what fertility preservation options exist for ...

A case report describes arginine vasopressin deficiency that emerged only after glucocorticoid therapy unmasked pembrolizumab-induced hypophysitis in a man with ...

A new review finds that pretreatment psychological distress is consistently associated with poorer outcomes after immune checkpoint inhibitor therapy, while ...

A retrospective study of 45 hepatocellular carcinoma patients found that intratumoral tertiary lymphoid structures were associated with disease control and ...

A new review explains how regulatory T cells are co-opted by ovarian tumors to suppress immunity, and how precision therapies ...

A case report in Oncoscience details a patient with metastatic lung cancer who developed severe Coombs-negative hemolytic anemia after pembrolizumab ...

A new narrative review finds that the clinical meaning of immune infiltration in bladder cancer depends on cell localization, functional ...

A new review maps how gut bacteria and their metabolites remotely reprogram lung tumors to shape immunotherapy response, resistance and ...

A 78-year-old woman developed hyperactive delirium with hallucinations and persecutory delusions during pembrolizumab therapy, and her symptoms fully resolved after ...

A case report details how a 46-year-old HIV-negative woman with idiopathic CD4+ lymphocytopenia developed progressive multifocal leukoencephalopathy and died despite ...

A retrospective study of 682 patients in Tianjin found 12.17 percent developed liver injury on immune checkpoint inhibitor therapy, with ...