Tag: Immune checkpoint inhibitors

A retrospective study of 682 patients in Tianjin found 12.17 percent developed liver injury on immune checkpoint inhibitor therapy, with ...

A new review finds that while cancer-associated fibroblasts clearly promote tumor growth and suppress natural killer cell activity in endometrial ...

An NIH-funded phase 1/2 trial will test whether JAK inhibitors can protect pancreatic insulin-producing cells in people who develop diabetes ...

A retrospective single-center cohort found that acute pancreatitis during immune checkpoint inhibitor therapy was associated with treatment disruption and substantially ...

A peer-reviewed study associated elevated circulating B cells before treatment with increased risk of immune checkpoint inhibitor–related colitis and found ...

A review of clinical and preclinical evidence finds that antibody–drug conjugates can improve outcomes with immune checkpoint inhibitors in several ...

A retrospective cohort of 331 initially diagnosed patients with HCC and Vp3/4 portal vein tumor thrombosis found a 61.3% objective ...

A Journal of Translational Medicine review outlines how mRNA-encoded antibodies, bispecific constructs, and transient CAR expression could overcome the manufacturing ...

A retrospective study of 2,409 patients found that baseline beta-1 selective beta-blocker therapy was independently associated with higher all-cause mortality, ...

A narrative review in Cancer Cell International outlines how artificial intelligence can integrate genomic, transcriptomic, imaging, and other multi-omics data ...

University of Pittsburgh researchers created a diet-based mouse model showing that fragile regulatory T cells, shaped by a Western-style diet ...

A single-center cohort study linked checkpoint inhibitor-containing therapy with longer unadjusted progression-free survival in advanced SMARCA4-deficient thoracic tumors, but adjusted ...

A meta-analysis of fourteen retrospective cohort studies associates TACE-HAIC combined with targeted therapy and immune checkpoint inhibitors with improved survival ...

An ancillary analysis of the Japanese phase III trial JCOG1013 found that a tumor proportion score of at least 1% ...

A qualitative study of 15 patients finds that fractures during immune checkpoint inhibitor therapy are viewed as "a small price ...

A network meta-analysis of six randomized trials in 5,838 patients finds that pembrolizumab plus belzutifan offers the strongest protection against ...

A 2026 review finds that JAK-STAT signaling suppresses antitumor immunity in breast cancer, but mixed clinical trial results expose challenges ...

A systematic review finds that gut microbes and metabolites may shape the liver immune environment associated with immunotherapy response in ...

In a two-center observational cohort of 120 patients with advanced NSCLC and COPD, higher serum IL-6 measured after six treatment ...

A prospective single-center cohort linked baseline thyroid autoantibodies and higher TSH to more immune-related thyroid dysfunction during advanced lung cancer ...