Tag: Immune checkpoint inhibitors

A matched cohort study found immune checkpoint inhibitors did not increase adverse events or worsen survival in cancer patients with ...

A systematic review and network meta-analysis of ten randomized trials evaluated the adverse event profiles of immune checkpoint inhibitor-based combination ...

A scientific review examines how cellular, vascular, and metabolic barriers disrupt immune coordination in solid tumors and outlines multi-targeted strategies ...

A narrative review synthesizes clinical evidence on immune checkpoint inhibitor-associated myocarditis, highlighting diagnostic pathways, mortality patterns, and immunosuppressive therapies.

A disproportionality analysis of the FDA Adverse Event Reporting System reveals distinct cutaneous toxicity signals between immune checkpoint inhibitors and ...

A review in Clinical and Experimental Medicine examines how mitochondrial metabolism and signalling govern tumour immune evasion and highlight potential ...

Depth of response and early tumor shrinkage serve as significant predictors of overall survival in patients receiving second-line or later ...

A retrospective study conducted at Kuopio University Hospital in Finland reveals that immune-related adverse events (irAEs) resulting from immune checkpoint ...

A new review finds AI-derived biomarkers show promising, though variable, performance in predicting cancer immunotherapy response across tumor types.

An exploratory analysis of the phase II PROMIT trial found that gut microbiome TOPOSCORE classifications failed to predict treatment outcomes ...

Spatial profiling of melanoma tumors reveals that lipid-associated macrophage neighborhoods drive immune exclusion and predict resistance to checkpoint inhibitor therapy.

Clinicians documented the rare concurrent emergence of rheumatoid arthritis and Sjögren's syndrome in a patient receiving nivolumab for recurrent gastric ...

An observational study links pre-treatment memory B-cell enrichment and heightened cellular activation to the development of immune-related adverse events in ...

A prospective multicenter cohort study evaluates whether plasma-derived extracellular vesicles can predict response to anti-PD-(L)1 therapies in patients with advanced ...

The Chinese Anti-Cancer Association has published an open access guideline standardizing diagnosis and treatment of respiratory injury caused by tumors ...

A review in the Journal of Translational Medicine examines how metabolic reprogramming enables regulatory T cells to drive immunosuppression in ...

A longitudinal immune monitoring study showed that combining tinostamustine with nivolumab was linked to preserved adaptive immune competence and antigen-specific ...

A new review argues that gut bacterial metabolites such as butyrate and indoles can be engineered as programmable drugs to ...

A new study links tumor-derived TNF-α, CCL4-high tumor-associated neutrophils, and suppressed T-cell activity to immunotherapy resistance in non-small cell lung ...

A new review finds checkpoint inhibitors are safe and effective for virologically suppressed people with HIV, while sub-Saharan Africa remains ...