Tag: Immune checkpoint inhibitors

A case report describes arginine vasopressin deficiency that emerged only after glucocorticoid therapy unmasked pembrolizumab-induced hypophysitis in a man with ...

A new review finds that pretreatment psychological distress is consistently associated with poorer outcomes after immune checkpoint inhibitor therapy, while ...

A retrospective study of 45 hepatocellular carcinoma patients found that intratumoral tertiary lymphoid structures were associated with disease control and ...

A new review explains how regulatory T cells are co-opted by ovarian tumors to suppress immunity, and how precision therapies ...

A case report in Oncoscience details a patient with metastatic lung cancer who developed severe Coombs-negative hemolytic anemia after pembrolizumab ...

A new narrative review finds that the clinical meaning of immune infiltration in bladder cancer depends on cell localization, functional ...

A new review maps how gut bacteria and their metabolites remotely reprogram lung tumors to shape immunotherapy response, resistance and ...

A 78-year-old woman developed hyperactive delirium with hallucinations and persecutory delusions during pembrolizumab therapy, and her symptoms fully resolved after ...

A case report details how a 46-year-old HIV-negative woman with idiopathic CD4+ lymphocytopenia developed progressive multifocal leukoencephalopathy and died despite ...

A retrospective study of 682 patients in Tianjin found 12.17 percent developed liver injury on immune checkpoint inhibitor therapy, with ...

A new review finds that while cancer-associated fibroblasts clearly promote tumor growth and suppress natural killer cell activity in endometrial ...

An NIH-funded phase 1/2 trial will test whether JAK inhibitors can protect pancreatic insulin-producing cells in people who develop diabetes ...

A retrospective single-center cohort found that acute pancreatitis during immune checkpoint inhibitor therapy was associated with treatment disruption and substantially ...

A peer-reviewed study associated elevated circulating B cells before treatment with increased risk of immune checkpoint inhibitor–related colitis and found ...

A review of clinical and preclinical evidence finds that antibody–drug conjugates can improve outcomes with immune checkpoint inhibitors in several ...

A retrospective cohort of 331 initially diagnosed patients with HCC and Vp3/4 portal vein tumor thrombosis found a 61.3% objective ...

A Journal of Translational Medicine review outlines how mRNA-encoded antibodies, bispecific constructs, and transient CAR expression could overcome the manufacturing ...

A retrospective study of 2,409 patients found that baseline beta-1 selective beta-blocker therapy was independently associated with higher all-cause mortality, ...

A narrative review in Cancer Cell International outlines how artificial intelligence can integrate genomic, transcriptomic, imaging, and other multi-omics data ...

University of Pittsburgh researchers created a diet-based mouse model showing that fragile regulatory T cells, shaped by a Western-style diet ...