Tag: Epithelial-mesenchymal transition

A laboratory study using Huh-7 cell cultures found that hepatitis B virus subgenotype A1 and its G1862T mutation alter cellular ...

A new integrative bioinformatic study reveals that immune checkpoint and epithelial-mesenchymal transition pathways interact context-dependently to shape the tumor microenvironment ...

In a mouse model of endometriosis, macrophage-derived migrasomes reached ectopic lesions and promoted fibrotic remodeling alongside TGF-β/Smad pathway activation.

Researchers found that miR-93-5p alleviates intrauterine adhesion by suppressing endometrial epithelial-mesenchymal transition through inhibition of Smad2 expression and phosphorylation.

Researchers developed a contrast-enhanced MRI radiogenomic surrogate reflecting a composite hypoxia, angiogenesis, and epithelial–mesenchymal transition transcriptional state that associates with ...

A laboratory study finds that sodium butyrate suppresses endometrial cancer cell growth by inhibiting thymidylate synthase and reprogramming pyrimidine metabolism ...

New research shows that the long non-coding RNA LINC00332 promotes epithelial-mesenchymal transition, cell migration, and paclitaxel resistance in colorectal cancer ...

Patient-derived gallbladder cancer organoids faithfully reproduced tumor genetics and showed drug sensitivities that tracked with patient survival in a preliminary ...

In a mouse cell-culture study, macrophage donor age rather than the age of circulating extracellular vesicles determined how well hypoxia-stressed ...

Researchers report that the long noncoding RNA KCNMB2-AS1, activated by the transcription factor FOXP3, promotes clear cell renal cell carcinoma ...

A new review in Cell Division details how colorectal cancer cells form their own blood-supply channels through vasculogenic mimicry, a ...

A new review proposes that mature tumor cells can dedifferentiate into cancer stem cells, acting as a non-genetic engine of ...

A new study links obesity-associated leptin levels to global DNA hypomethylation and altered EMT gene expression in breast epithelial cells, ...

A prospective case-control study found preoperative serum CXCL2 discriminated endometrial cancer from benign gynecologic disease with an AUC of 0.923, ...

A new study reports that the enzyme PLA2G4A promotes non-small cell lung cancer proliferation, survival and metastasis through an SP1–IL-1β–MAPK–HSF1 ...

A reanalysis of two independent bladder cancer cohorts found 4,102 genes with concordant tumor-associated expression changes and confirmed five candidates ...

Migrating cancer cells shed large vesicles called MoVes that carry whole genomic DNA, organelles and EMT-linked proteins, according to a ...

Folate-functionalized chitosan nanoparticles carrying an Ailanthus excelsa stembark extract restored miR-34a and suppressed NOTCH1 signaling, reducing tumor growth, metastasis and ...

A review describes how heat shock proteins influence tumor survival, metastasis, immune escape, and the design of future targeted cancer ...

A new review explains how barrier disruption, alarmin release and epithelial repair programs drive asthma pathology and may offer new ...