Single-nucleus transcriptomic profiling of human amyotrophic lateral sclerosis tissues reveals marked blood-spinal cord barrier breakdown and specialized perivascular fibroblast remodeling ...
Researchers 3D bioprinted heart tissue patches containing human endothelial cells and found that those with vessel-like networks supported more aligned ...
Researchers built a cell-lined silicone blood vessel large enough to hold a real stent and quantified how endothelial cells recolonize ...
A human stem-cell study shows that static membrane inserts and a flowing microfluidic blood-brain barrier chip give strikingly different answers ...
A new review maps how m6A RNA methylation acts differently across cell types and wound phases, and outlines biomaterial strategies ...
A mouse study reports that CD34+ telocytes promote angiogenesis and wound healing by signaling to endothelial cells through Sema3c and ...
A six-gene endothelial cell signature built from single-cell RNA sequencing data predicts survival outcomes and reveals distinct tumor microenvironment communication ...
Chemically modified BRD4 degraders MZ-1-ME and SIM-1-ME showed enhanced protein degradation and growth inhibition in a KSHV-infected endothelial cell model ...
A new review in Biological Research surveys cardiac stem and progenitor cell populations, finding that classic markers c-kit and Sca-1 ...
A newly published protocol details a three-component tumor organoid co-culture system with 3D live-cell imaging that quantifies single-cell dynamics of ...
A dynamic bicellular in vitro model linked by a fluidic circuit reproduced vascular disruption and fibroblast changes when endothelial cells ...
A new protocol generates tunable human vascular organoids in six days by inducibly activating the transcription factors ETV2 and NKX3.1 ...
A cell-culture study finds that intracellular glutathione availability, rather than vitamin C supplementation, determines how endothelial cells survive exposure to ...
A new study reports that the endothelial protein CCDC92 promotes STAT1 degradation through the proteasome and that its loss, linked ...
A cell study finds that WTAP upregulates KDR through m6A modification, protecting human brain microvascular endothelial cells from angiotensin II-induced ...
Scientists have created a CTRP9-CreERT2 knock-in mouse line whose tamoxifen-inducible reporter selectively labels microvascular endothelial cells in heart, skeletal muscle, ...
Scientists report that co-expressing the AP-1 family transcription factors FOSB and JUND induces functional ABCB1 expression and remodels transport programs ...
An integrative ATAC-seq and RNA-seq study of induced endothelial cells from capillary malformation patients identifies inflammation-associated chromatin remodeling and distal ...
Co-culturing human brain endothelial cells with pericytes activates AKT and ERK insulin signaling, raises TIMP1 and collagen-IV, inhibits MMP activity ...
A new review argues that the atherogenic outcome of S1PR1 signalling depends on cell type, ligand presentation and inflammatory context ...
