Most Secondary Chest Tumors in Head and Neck Cancer Are Metastases, Study Finds
Genomic analysis of 71 tumors from 20 patients shows most secondary chest lesions in head and neck squamous cell carcinoma ...
Tag: EGFR
Computer screen sifts animal peptides for breast cancer drug leads
A computational pipeline filtered about 1,500 animal-derived antimicrobial peptides down to three candidates that dock strongly against the breast cancer ...
Low Phosphate on Admission Flags Higher Risks of Kidney Injury and Death in Hospitalized Adults
A retrospective study of 40,884 hospitalized adults found that low admission serum phosphate was independently associated with in-hospital acute kidney ...
CUL3 mutations reshape NRF2 control in TP53-mutant lung cancer
A multi-cohort genomic and molecular dynamics study links CUL3 mutations to TP53-associated NRF2 dysregulation in EGFR-driven non-small cell lung cancer ...
Herbal Blend Cuts Blood Sugar and Inflammation in Type 2 Diabetes Trial
A 24-week controlled study found that a standardized eight-plant botanical formulation significantly reduced HbA1c, insulin resistance and inflammation in adults ...
Network Analysis Pinpoints Five Hub Genes Steering Hodgkin Lymphoma Pathways
An integrative bioinformatics study of 3,180 Hodgkin Lymphoma-associated genes identified TP53, STAT3, AKT1, EGFR and IL6 as the most highly ...
Deep learning model predicts growth of lung ground-glass nodules
A multimodal deep learning framework combining CT radiomics, clinical variables, and EGFR status predicted growth trends of pulmonary ground-glass nodules ...
HSP90 Chaperone Isoforms Emerge as Precision Targets in Lung Cancer
A new review maps how the four HSP90 chaperone isoforms play distinct roles in lung cancer progression and drug resistance, ...
Rare Sarcoma Arising From Castleman Disease Tied to Pemphigus and Poor Survival
A six-case retrospective study found follicular dendritic cell sarcoma arising from Castleman disease was frequently complicated by paraneoplastic pemphigus and ...
Weekly tocilizumab dosing linked to lower rheumatoid arthritis activity in real-world study
A 52-week retrospective observational study of 58 Japanese rheumatoid arthritis patients found that disease activity declined after escalating subcutaneous tocilizumab ...
Curcumin and Pentoxifylline Show Modest Kidney Benefits in Six-Month CKD Trial
An open-label randomized trial in Egypt found that six months of adjunctive curcumin or pentoxifylline in stage 3–5 chronic kidney ...
Chronic Kidney Disease Affects Nearly 15% of Fulni-ô Indigenous Adults in Brazil
A cross-sectional study of 569 Fulni-ô Indigenous adults in Brazil estimated a chronic kidney disease prevalence of 14.9%, with older ...
JEEPERS Corrects Hidden Methylation Errors in Cell-Free DNA Sequencing
A new computational framework called JEEPERS detects and corrects methylation errors caused by jagged ends in cell-free DNA, improving cancer ...
Review maps key signaling pathways driving oral squamous cell carcinoma and targeted therapies
A new open-access review in Discover Oncology surveys the key signaling pathways in oral squamous cell carcinoma and the targeted ...
Reduced Kidney Function Found in Nearly One in Eight Tested South African Adults
A national analysis of South African public-sector laboratory records found eGFR below 60 in 12.69 percent of tested adults, with ...
Obesity affects one in four adults in Polish city study, with waist measures flagging hidden risk
A population-based study of 3,524 adults in Białystok, Poland, found 63.5% had overweight or obesity by BMI and that combining ...
Ayurvedic Hydro-Distillate Guduchi Arka Profiled by GC–MS and Network Pharmacology
A new study combined pharmacopoeial quality testing, GC–MS profiling and computational network pharmacology to standardise the Ayurvedic hydro-distillate Guduchi Arka, ...
Diabetes, hypertension and dyslipidemia raise kidney disease risk in people with HIV
A large Kaiser Permanente cohort study found that people with HIV developed chronic kidney disease at 2.52 times the adjusted ...
Women Remain a Small Minority in Tafamidis-Treated Amyloid Heart Disease Cohort
A pooled analysis of 1924 tafamidis-treated patients found women made up 11.1 percent of the cohort, more often carried hereditary ...
Cyprus Ties NICE Kidney Guideline to Better CKD Care in First Year
A one-year study in Cyprus found that introducing contextualized NICE-based CKD quality indicators into the national health system was associated ...
POPULAR NEWS
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Case Report Explores Caplacizumab in Late-Diagnosed Congenital Thrombotic Thrombocytopenic Purpura
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Multitask Cambrian Model Improves Protein Melting Temperature Prediction
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Vasopressors Exert Divergent Immunomodulatory Effects Across a Spectrum in Septic Shock
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Study Identifies Key Drivers Shaping Salmonid Gill Microbiomes in Aquaculture