Review details advances in vaginal drug delivery systems
A narrative review in the Future Journal of Pharmaceutical Sciences analyzes over 120 studies on how nanocarrier systems overcome physiological ...
Tag: Clinical Translation
Microarray Patches Offer Needle-Free Drug Delivery While Facing Scale-Up Realities
A critical narrative review evaluates the technological advances, manufacturing hurdles, and clinical trial frameworks governing microarray patches for transdermal drug ...
AI Predicts Orthodontic Root Resorption but Methodological Gaps Limit Clinical Translation
A scoping review reveals that while deep learning models demonstrate high accuracy in identifying orthodontically induced root resorption, methodological risks ...
Gastric Cancer Metastasis Patterns Reveal Distinct Molecular Targets
A new review in Annals of Gastroenterological Surgery proposes treating gastric cancer metastasis as distinct patterns, identifying route-specific biomarkers and ...
Review proposes AI-driven BCI framework for Alzheimer’s care
A review in Alzheimer's Research & Therapy proposes an AI-driven brain-computer interface framework to enhance diagnosis and therapeutic intervention for ...
Microbiome Scientists Ask What Evidence Will Turn Discoveries Into Medicine
The 13th World Congress on Targeting Microbiota in Málaga will examine what evidence is needed to translate microbiome research into ...
Supplemental Oxygen Masks Postoperative Opioid Respiratory Risks
A new review in Frontiers in Medicine highlights how supplemental oxygen can mask signs of opioid-induced respiratory depression, complicating postoperative ...
3D Printed Scaffolds Still Fall Short on Vascularization for Bone Repair
A new review argues that 3D-printed bone scaffolds still lack the functional, perfusable vascular networks needed for clinical translation.
AI Reads Ovarian Ultrasounds Well, But Bias and Thin Validation Hold It Back
A systematic review of 65 studies finds AI models for PCOS ultrasound diagnosis report high accuracy but suffer from substantial ...
AI-designed CAR binders push cancer stem cell immunotherapy toward safer targets
A new review maps how artificial intelligence could overcome resistance and safety barriers in cancer stem cell-targeted cellular immunotherapy, while ...
Gut microbe molecule butyrate proposed as shield for children’s sepsis kidney injury
An editorial in World Journal of Pediatrics argues that butyrate, a short-chain fatty acid made by gut bacteria, is a ...
Extracellular vesicles emerge as biomarkers and therapies for vascular dementia
A structured narrative review maps extracellular vesicle evidence in vascular cognitive impairment and dementia, finding therapeutic research still largely preclinical ...
Orthopaedic implant coatings show promise but lack proof of broad clinical benefit, review finds
A review of 27 primary reports finds experimental evidence for implant coating activity but no general clinical advantage from coating ...
Ethosomal nanocarriers aim to reprogram skin cancer microenvironment through transdermal drug delivery
A new review argues that ethanol-rich lipid vesicles called ethosomes could deliver anticancer drugs deep into skin tumours while reshaping ...
Nanocarriers May Boost Berberine’s Anticancer Activity in Triple-Negative Breast Cancer
A narrative review finds nanoformulations improved berberine's delivery and preclinical efficacy in triple-negative breast cancer, while human evidence remains lacking.
Mapping How Stem Cell Grafts Behave Inside the Injured Spinal Cord
A new review argues that stem cell grafts can protect tissue and communicate with host circuits in selected spinal cord ...
Smart Nanoparticles Aim to Carry Brain Tumor Drugs Past the Blood–Brain Barrier
A new review details how stimuli-responsive and biomimetic nanoparticles are being engineered to cross the blood–brain barrier and deliver therapy ...
Radiopharmaceutical Design Shifts Focus from Peak Yield to Robustness
A position paper argues that radiochemical robustness, not just peak radiochemical yield, should be a co-equal design criterion in radiopharmaceutical ...
Plant compounds may rewire immune metabolism in heart disease, evidence still thin
A new review maps how plant-derived compounds might modulate immune-cell metabolism in cardiovascular disease, while stressing that most evidence remains ...
Lipid nanoparticles emerge as leading siRNA carriers for liver cancer therapy
A new review outlines how lipid-based nanomedicines could deliver pathway-specific siRNA to treat hepatocellular carcinoma, highlighting delivery design, preclinical candidates ...
