Tag: Cancer immunotherapy

A 2026 review proposes that bacteriophage-derived delivery, barrier-breaching and immune-stimulation features could help oncolytic viruses penetrate cold tumors and stimulate ...

Kansai Medical University Hospital gave the first worldwide dose of investigational CD25-directed antibody drug conjugate DS1025 in a global Phase ...

A retrospective study of 38 patients with advanced HPV16-positive cancers linked baseline and early serum protein measurements to outcomes from ...

A review finds that three-dimensional cultures and organ-on-a-chip devices reveal context-dependent neutrophil behavior and provide preclinical platforms for testing neutrophil-based ...

A 2026 review summarizes recurrent molecular alterations, immune suppression, multimodal imaging and current treatment strategies for primary cardiac angiosarcoma, a ...

A nine-patient phase I trial found that TIGIT-disrupted NK510 could be combined with PD-1 blockade without observed dose-limiting toxicities in ...

A single-arm phase II trial of 40 patients with locally advanced esophagogastric junction adenocarcinoma reported high pathological response rates, manageable ...

An interpretable deep learning model called SPACER reads spatial transcriptomics data to reveal the molecular and spatial rules that govern ...

A new review in Holistic Integrative Oncology charts the rapid rise of antibody–drug conjugates in solid tumors while detailing the ...

A systematic bibliometric review of more than 3,200 publications reveals that tumor immunometabolism research has surged since 2020, shifting from ...

A new review charts how in vivo CAR-T engineering could transform customized living drugs into scalable, off-the-shelf genetic medicines.

A new review in Molecular Cancer synthesizes how liquid-liquid phase separation shapes radiosensitivity, immune evasion, and treatment resistance in cancer.

A new review highlights how induced pluripotent stem cells are being engineered into immune cells, cancer vaccines, and tumor models ...

A new review reveals how neutrophils can either enhance or undermine oncolytic virus therapy through N1/N2 polarization, virus delivery, and ...

A sweeping new review in Molecular Cancer maps the PD-1/PD-L1 axis from immune evasion mechanisms to next-generation therapeutics, offering a ...

UCLA researchers used a genome-wide CRISPR screen to identify the Cullin-5 RING E3 ligase complex as a key driver of ...

A new review in Molecular Biology Reports surveys how engineered CAR-T, TCR, TIL, NK and NKT cell therapies, gene editing, ...

Roche researchers validate a human 3D immune-containing colorectal cancer assembloid platform that captures interferon-gamma signaling, uncovers fibroblast plasticity, and demonstrates ...

A novel intravenous STING agonist, BI 1703880, synergises with radiotherapy and checkpoint inhibitors to generate durable anti-tumour immunity in preclinical ...

Researchers propose a closed-loop framework that unites AI-driven sequence design, molecular dynamics simulation, and experimental validation to rationally engineer high-affinity, ...