Tag: Cancer immunotherapy

A Science Bulletin review outlines how multimodal artificial intelligence integrating molecular, cellular, and clinical data could refine immunotherapy decisions while ...

A recombinant overlapping peptide vaccine targeting HPV16 E7, combined with 4-1BB agonist antibody, eradicated established tumors in most treated mice ...

A new review maps how engineered DNA and RNA aptamers could enable targeted delivery and tumor microenvironment remodeling in precision ...

An NIH-funded phase 1/2 trial will test whether JAK inhibitors can protect pancreatic insulin-producing cells in people who develop diabetes ...

A mouse breast cancer study found that CD40-stimulated B cells recruited CD8+ T cells into tumors, influenced their organization and ...

A retrospective single-center cohort found that acute pancreatitis during immune checkpoint inhibitor therapy was associated with treatment disruption and substantially ...

A peer-reviewed study associated elevated circulating B cells before treatment with increased risk of immune checkpoint inhibitor–related colitis and found ...

An animal study by City of Hope researchers shows that modular CAR T cells can accept engineered adaptors after treatment, ...

A review of clinical and preclinical evidence finds that antibody–drug conjugates can improve outcomes with immune checkpoint inhibitors in several ...

A Journal of Translational Medicine review outlines how mRNA-encoded antibodies, bispecific constructs, and transient CAR expression could overcome the manufacturing ...

A retrospective study of 2,409 patients found that baseline beta-1 selective beta-blocker therapy was independently associated with higher all-cause mortality, ...

The 2026 World Medical Innovation Forum showcased experimental precision-frozen pig organs, a preclinical pancreatic-cancer immunotherapy, AI-enabled cardiovascular screening and a ...

University of Pittsburgh researchers created a diet-based mouse model showing that fragile regulatory T cells, shaped by a Western-style diet ...

A review in Journal of Translational Medicine describes how dysregulated RNA editing suppresses tumor immune recognition and how programmable RNA ...

A preclinical study reports that the IL-13E13Y-based T-cell engager 313TE linked IL-13Rα2-positive tumor cells to T cells, promoting receptor-dependent killing ...

A retrospective Nepalese cohort of 31 patients associated 20- or 40-milligram nivolumab with responses across advanced cancers, but uncontrolled evidence ...

A 2026 review finds that JAK-STAT signaling suppresses antitumor immunity in breast cancer, but mixed clinical trial results expose challenges ...

A 2026 review finds that TCR-engineered T cells have entered early clinical testing for hepatocellular carcinoma, but safety, antigen heterogeneity ...

A systematic review finds that gut microbes and metabolites may shape the liver immune environment associated with immunotherapy response in ...

A narrative review identifies prostate cancer stem-like cells as plausible contributors to treatment persistence and relapse while concluding that most ...