Biology

In a Drosophila model of Parkinson's disease, neuronal overexpression of the polyamine enzyme SAT1 reduced alpha-synuclein protein levels, modified stress-response...

A preclinical study reports that ginseng-derived ginsenoside Rg3 binds Glut1 on tumor-associated macrophages, reprograms their metabolism, and enhances anti-PD-1 therapy...

Researchers identified the TLR2/TLR4-binding sequences of the matrix protein biglycan and showed that synthetic peptides carrying these motifs reduce inflammation...

A multi-omics study computationally nominates the gut microbe Lachnoclostridium and the gene ENO1 as candidates in inflammatory myopathies, with cell...

A new review maps how protein arginine methyltransferases both cooperate and antagonize one another in tumors, arguing that multi-target and...

A multi-omics study of three-flowered maple links coppicing to activation of the isoflavonoid biosynthesis pathway and correlated regenerative traits.

Knocking down CISD2 suppresses gastric cancer cell growth and induces ferroptosis through inhibition of the mTOR/SREBF1/SCD1 axis and GPX4 downregulation,...

A decade after the 2013 Rim Fire burned a long-unburned Yosemite forest, shrubs favored fire-sensitive white fir regeneration over fire-tolerant...

A new in vitro study finds that mesoporous silica and graphene oxide both reduce cell viability and significantly increase mutations...

A study of 40 neonatal goat kids with hemorrhagic abomasitis found Escherichia coli in 75 percent of cases, with phylogroup...

A Biological Research review synthesizes how climate change affects fruit tree physiology and how genotype diversity and rootstock selection can...

A longitudinal study of healthy periparturient Holstein cows found that prepartum rumen microbial community structure was associated with later milk...

A validated polydimethylsiloxane-based workflow captures time-resolved fungal volatile profiles while addressing solvent bias, sampling configuration and sorbent reuse.

A study of 1,032 sensor-monitored Japanese Black cattle finds behavioral traits are weakly heritable and genetically, if modestly, correlated with...

An in vitro study reports a chitosan nanoparticle and GelMA hydrogel platform that releases resveratrol faster at acidic pH and...

Two lactic acid bacteria strains from healthy Lichuan horses inhibited equine Clostridium perfringens in vitro and reduced disease signs in...

A new study reports that NAT10-mediated mRNA acetylation and USP19-mediated deubiquitination jointly stabilize CDH3, promoting colorectal cancer progression and immune...

Camera traps have recorded two golden jackals in King Abdulaziz Royal Reserve, the first confirmed record of the species in...

A re-analysis of prostate cancer reporter assay data shows computational annotations poorly predict measured regulatory activity, while ovarian risk variant...

A techno-economic analysis of recombinant lipase production in Pichia pastoris finds that secreted protein titre and downstream recovery, not feedstock...