Biology
Non-native plants’ mycorrhizal strategies shift across biomes and disturbance levels
A global study has challenged one of ecology’s most persistent assumptions about invasive plants: that their success is consistently powered...
Japanese Colorectal Cancer Reveals Prevalence, Timing, and Microbiome Signatures of Colibactin Mutations
Colorectal cancer is often described as a disease written into the genome, but the authors of a new study argue...
New CAF Population Directs Highly Suppressive Regulatory T Cells in Lung Tumors
A previously unrecognized population of cancer-associated fibroblasts appears to act as a spatial organizer for immune suppression in lung cancer,...
Protein nanocrates overcome air–water interface artifacts in cryo-EM
Cryo-electron microscopy has transformed structural biology by allowing scientists to visualize proteins and other biological machines at near-atomic resolution. Yet...
Nucleosomes and IDRs Restrain GCN4’s Promiscuous Binding on Minichromosomes
A new study is reshaping the way scientists understand how transcription factors find their targets inside the crowded genome. Researchers...
Framework combines multiple evidence streams to discover biomarkers in small-sample time-series transcriptomics
Small-sample RNA-sequencing studies often promise a window into the molecular changes that accompany disease, treatment response, or infection. Yet when...
Photoprotection, carbon reallocation drive Dendropanax trifidus drought recovery in future climates
A subtropical tree has revealed how forests may survive a future defined by hotter temperatures, rising atmospheric carbon dioxide and...
Rainfall Shapes Rhizosphere Microbial Communities Across Two Alpine Wetland Types
Rainfall is doing more than replenishing water in alpine wetlands: it may be steering the microscopic communities that live around...
Hunter-gatherers sleep as long as modern humans, but at different times
The idea that every adult needs exactly eight hours of sleep has become one of modern wellness culture’s most durable...
Study reveals how PRC2 guides preimplantation development and primordial germ cell fate
A new study has revealed that the epigenetic regulator PRC2 performs different, stage-specific jobs during the earliest phases of mammalian...
Tropical Forest Regeneration Costs and Ecological Benefits Vary Widely
Tropical forests may be able to return naturally across millions of square kilometres of degraded land, offering a powerful but...
How Aging and Alzheimer’s Reshape Human Microglia and Brain Perivascular Macrophages
Alzheimer’s disease has long been described through the lens of neurons: the loss of synapses, the accumulation of amyloid-β plaques,...
TIF1γ Maintains Regulatory T-Cell Stability During Inflammation
Regulatory T cells, commonly known as Treg cells, are the immune system’s essential peacekeepers. They suppress excessive immune reactions, limit...
NicheTrans Enables Spatially Aware Translation Across Omics Data
Spatial biology has promised a more complete view of how cells behave inside tissues, but that promise has often come...
Hydrophobic FG-nucleoporin interactions expand post-mitotic nuclear pores into selective transport channels
The nucleus is often portrayed as a fortress, sealed off from the rest of the cell by a protective membrane....
Two Decades of Induced Pluripotent Stem Cells: From Pluripotency to Reprogramming
Twenty years after scientists first demonstrated that a mature cell could be pushed backward into a stem-cell-like state, induced pluripotent...
Study Retracted on Desferrioxamine B Improving Peanut Oil Content, Nutrient Uptake, Growth
The scientific record surrounding a study on a microbial iron-chelating compound and peanut productivity has been reset after the publication...
Scientists identify environmental signals triggering bears’ hibernation
Virginia Tech researchers have uncovered new evidence that black bear hibernation is governed by a complex interaction between temperature, daylight,...
Brain mega-enhancers compartmentalize transcriptionally active long genes
A previously unrecognized layer of genome organization has been identified in the mammalian brain, where exceptionally long genes and the...
hnRNPK condensates boost enhancer–promoter looping and RNA polymerase II recruitment
Scientists have identified a molecular organizer that helps connect distant regulatory regions of the genome with the genes they control,...