Tag: Spatial transcriptomics

A sweeping methodological review published in Frontiers in Oncology argues that the explosion of public-omics research in gastric cancer has ...

Integrated transcriptomic and cell-line analyses link GSTK1 expression to favorable gastric cancer prognosis and to IL-6/JAK2/STAT3 signaling, glycolysis-related proteins, and ...

A mouse study from Institute of Science Tokyo shows the YAP1–TEAD–TET1 epigenetic pathway can drive hepatocellular carcinoma without canonical driver ...

A spatial transcriptomics study of 16 MASH patients and eight controls maps compartment-specific CYP450 suppression, immune activation, and disrupted cell-cell ...

A 2026 Review argues that osteosarcoma survival and lung spread depend on stage-specific rewiring of extracellular-matrix signaling rather than one ...

An AI-driven single-cell and spatial multi-omics study defines three glioma ecosystem states and shows that a hypoxic myeloid-mesenchymal state independently ...

A multi-omics study combining genomics and spatial transcriptomics finds that BRCA-mutated high-grade serous ovarian cancers show stronger interferon and inflammatory ...

A Nature Methods benchmark of 11 segmentation methods across 15 spatial transcriptomics datasets shows that algorithm and platform choices substantially ...

The openDVP framework combines microscopy, spatial analysis and proteomics in proof-of-concept human placenta, lung-cancer and relapsed breast-cancer studies.

A computational framework linked spatial gene-expression gradients to net-production direction under steady-state and positive-flow assumptions, with reproducible directions in human ...

An exploratory multi-omics analysis links regulatory T-cell and proliferation programs to anti-PD-1 response in endometrial cancer, but the treatment comparison ...

A computational benchmarking study found that SubPoE delivered the strongest average spatial-domain clustering results across eight paired spatial multi-omics datasets ...

A small clinical study linked lipid metabolism and mitochondrial respiration to low CD8-positive T-cell infiltration in esophageal adenocarcinoma using spatial ...

A public-data multi-omic study found a reproducible epithelial program shared by pancreatic ductal adenocarcinoma and ischemic stroke, while related myeloid ...

A secondary analysis of 21 rat spatial-transcriptomic sections found a positive but statistically uncertain association between dECM deployment and greater ...

A 2026 review proposes modernizing the murine Ehrlich carcinoma model with multi-omics, single-cell profiling, CRISPR experiments and RISC-centered analysis while ...

A single-embryo spatial transcriptomic and metabolomic atlas maps stage-specific molecular programmes across organ primordia in a Carnegie stage 12 human ...

A mouse study found that embryonic thalamic progenitors segregate into sensory and motor-associative lineages, with Sp9 perturbation reducing formation of ...

A Mini Review finds that AI-assisted integration of genomic and spatial data may reveal lesion-specific biology in ovarian cancer liver ...

University of Osaka researchers mapped the earliest cellular events of ANCA-associated glomerulonephritis and showed that modified antibodies reducing Fcγ receptor ...