Tag: single-cell RNA sequencing

A new EMBO Reports study shows that the lncRNA Carmn sustains basal stemness across mammary, salivary, and lacrimal glands by ...

A multimodal AI model built from routine pathology slides predicts bladder cancer survival and led researchers to RTN3, which drives ...

A new single-cell RNA sequencing study maps how topical imiquimod remodels splenic immune cells in a lupus-like mouse model, revealing ...

A secondary analysis of single-cell data finds that progenitor-enriched radial glia-like cells and cycling neural progenitor cells show the strongest ...

Researchers identified a POSTN-expressing tumor-associated endothelial cell subset that promotes and predicts pulmonary metastasis in osteosarcoma.

Sequencing of 11 colorectal cancer patients shows peritoneal metastases often arise early, polyclonally, and through metastasis-to-metastasis seeding.

A phase 2 trial reports that camrelizumab plus famitinib produced tumor shrinkage in 42.9 percent of patients with advanced pulmonary ...

An exploratory study links PET microplastic exposure to immune and signaling changes in recurrent pregnancy loss, identifying YWHAZ as a ...

Longitudinal single-cell sequencing of a patient-derived prostate cancer model shows that treatment-induced neuroendocrine transdifferentiation proceeds through a transient mesenchymal gateway ...

Researchers built a seven-gene tumor stemness signature from single-cell and bulk transcriptomic data that predicts survival, immunotherapy response, and oxaliplatin ...

A new Cellular Oncology study reports that the tumor suppressor TNFAIP3 restrains lactylation-linked DNA damage repair and increases ovarian cancer ...

A new study finds that the neuronal protein SORT1 preserves endosomal balance, calms microglial inflammation and improves cognition in Alzheimer's ...

Preclinical work shows the pan-RAS inhibitor RMC-6236 triggers adaptive EGFR feedback in KRAS-mutant cholangiocarcinoma cells, and pairing it with cetuximab ...

A reanalysis of two independent bladder cancer cohorts found 4,102 genes with concordant tumor-associated expression changes and confirmed five candidates ...

A mouse and human study identifies an Htr2b-positive macrophage subset in the ischemic brain whose serotonin-driven lysosomal activity supports debris ...

Researchers have introduced scDECA, a dual-encoder cross-attention framework that combines raw gene expression, pretrained gene priors and local structure to ...

A computational study built a gut microbiota–metabolite–host gene score that stratified rheumatoid arthritis patients into two molecular subtypes and predicted ...

A new study links tumor-cell RNF128 to reduced CD8-positive T-cell infiltration and poorer immune checkpoint blockade responses in bladder cancer.

An integrative analysis of bulk and single-cell transcriptomic data identifies ENO1 as a reproducibly upregulated metabolic factor associated with CD4+ ...

A 20-gene folate metabolism signature predicted hepatocellular carcinoma survival in some cohorts but failed in another, and the glutathione synthetase ...