Tag: RNA sequencing

A systematic review of 28 RNA sequencing studies shows biological pathway convergence in diabetic kidney disease despite substantial methodological heterogeneity.

In a mouse and cell model of alcoholic cardiomyopathy, researchers found that reduced DBT gene activity promoted copper accumulation and ...

Anastrepha acris larvae tolerate the toxic Apple of Death fruit through intact midgut barriers, reprogrammed metabolism and a phenolic-tolerant core ...

Researchers used low-frequency sound waves to assemble human mesenchymal stromal cell spheroids into stable rings within fibrin hydrogels and showed ...

Whole-blood transcriptomics in a randomized phase 2 trial sub-study found distinct early gene expression changes with linezolid-containing tuberculosis regimens and ...

A new review argues that peripheral blood immune signatures, analyzed through multi-omics and genetic methods, could enable earlier and more ...

Scientists built an inducible human cell line that overproduces TDP-43, triggering toxicity, mislocalization, and gene expression changes that overlap with ...

RNA sequencing of 18 canine brain tumors reveals 45 genes expressed at different levels in French bulldogs compared with boxers ...

A comparative transcriptomic study finds that tolerant highland barley genotype L86 shows broader transcriptional activation of antioxidant, metabolic, and regulatory ...

A one-year Xinjiang field trial found that organic fertilizer combined with a composite microbial inoculant raised cotton photosynthesis and seed ...

Japanese researchers have established the first patient-derived organoid model of canine nasal carcinoma, showing variable drug sensitivities among tumor lines ...

RNA sequencing of fragile X model mice identified the proteins NDN and IDE as strongly upregulated candidate tissue biomarkers, with ...

An integrative RNA sequencing and machine learning study identified a seven-gene signature and key liver cell subpopulations associated with advanced ...

Genome sequencing of two siblings with adult-onset leukodystrophy uncovered a novel 270 kb deletion upstream of LMNB1 that removes a ...

A new study reports that dihydroartemisinin suppresses melanoma by promoting ubiquitination and proteasomal degradation of the transcription factor SP1.

A new review argues that only metatranscriptomics can distinguish which gut antibiotic resistance genes are actively transcribed from the larger ...

A new study in Caenorhabditis elegans reports that the ginseng component ginsenoside Rg1 slows aging in the worms by activating ...

A CRISPR screening-informed five-gene signature identifies liver cancer patients with poor sorafenib response, and ciclesonide emerges as a candidate drug ...

Folate-functionalized chitosan nanoparticles carrying an Ailanthus excelsa stembark extract restored miR-34a and suppressed NOTCH1 signaling, reducing tumor growth, metastasis and ...

In a rat model of pulmonary arterial hypertension, surgically cutting the cervical sympathetic trunk lowered lung pressures and reshaped transcription ...