Adolescent Oxycodone Exposure Boosts Adult Opioid Self-Administration in Female Mice
A mouse study finds adolescent oxycodone exposure increases adult remifentanil self-administration in females but not males, with sex-specific gene expression ...
A mouse study finds adolescent oxycodone exposure increases adult remifentanil self-administration in females but not males, with sex-specific gene expression ...
An integrated sequencing analysis identified MKI67, MIPEP and CCNA2 as candidate prognostic biomarkers for biochemical recurrence risk in prostate cancer.
A study in Animal Microbiome reports that breed mainly shapes jejunal gene expression while housing system mainly shapes gut microbial ...
Ossabaw pigs fed a high-fat, high-fructose diet gained weight but showed normal metabolic blood markers, with distinct transcriptional responses in ...
A new study shows that the stress sensors ATF4 and ATF6 coordinate transcriptional and metabolic responses to glucose deprivation in ...
In a mouse model of multiple system atrophy, oligodendroglial alpha-synuclein drives early ventral midbrain transcriptional changes in mitochondrial, metabolic and ...
Mice injected with bacterial endotoxin showed suppressed STAT1 signaling in splenocytes stimulated with interferon-gamma a day later, a new study ...
A genomic study of temporal cortex tissue identifies hundreds of exon-skipping events that separate Alzheimer's disease from progressive supranuclear palsy, ...
A new study reports that Cinnamomum tamala essential oil, dominated by cinnamaldehyde, killed unfed larvae, nymphs and adults of the ...
A new review in Molecular Biology Reports summarizes how exosome-based diagnostics are advancing across oncology, neurology, cardiology and infectious disease, ...
Researchers used optogenetic melanopsin stimulation in HeLa cells to show that the timing pattern of light-evoked calcium signaling selectively shapes ...
The ATR inhibitor AZD6738 reversed about 57% of the LPS-induced inflammatory gene program in mouse corneas and suppressed an NF-κB-centered ...
A paired tissue study of 11 patients finds that microRNA patterns tied to apoptosis and fibrosis remain largely unchanged after ...
A laboratory study of pediatric and adult liver organoids found higher Omicron viral RNA accumulation and a stronger innate immune ...
A multi-omics study of 191 wheat accessions associated a sucrose-synthase gene and carbohydrate metabolism with yield stability and low-nitrogen tolerance.
An experimental comparison of 17 autism-risk mouse lines identified two opposing brain-gene activity states that varied with sex, development and ...
A study of 75 people found that blood RNA patterns were more strongly associated with differences in cognition, tremor severity ...
A Drosophila study shows that an elevated Myc-to-Max ratio, rather than absolute MYC abundance, switches eye progenitors toward a wing ...
Researchers identified a stable major locus on wheat chromosome arm 4BS that influences drought tolerance during wheat germination and increases ...
A laboratory study of primary human lung fibroblasts finds that senescent fibrotic cells from idiopathic pulmonary fibrosis lungs activate antiviral ...
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