Patient-derived PSP-RS midbrain organoids show selective loss of respiratory reserve, coordinated electron transport chain remodeling, persistent oxidative stress, and broad ...
A systematic review and meta-analysis finds that electroacupuncture preconditioning is associated with reduced myocardial injury and favorable mitochondria-associated changes in ...
A study in Cell Biology and Toxicology shows that a darunavir-analogue precursor enhances tamoxifen response in breast cancer by inducing ...
Infection with yellow fever virus induces distinct stress granules enriched with mitochondrial proteins while viral capsid interactions with G3BP1 delay ...
A new study links smoking-associated cadmium to JNK2 activation in neurons, driving mitochondrial dysfunction and APP accumulation relevant to Alzheimer's ...
A multi-omics Mendelian randomization analysis identified 13 candidate mitochondrial-related genes linked to congenital heart disease susceptibility, with POLG and EARS2 ...
A scientific review evaluates the malate–aspartate shuttle as a candidate redox–bioenergetic hub in gastric atrophy and precancerous disease progression.
Researchers have found that overexpressing the protein FRZB restores mitochondrial function and rescues the bone-forming capacity of periodontal ligament stem ...
A new review links age-driven disruptions in bone cell metabolism to osteoporosis and maps emerging therapies targeting NAD+ decline, mitochondrial ...
A narrative review links mitochondrial breakdown, neuroinflammation, and endocrine stress responses within an integrative model of perinatal hypoxic-ischemic brain injury.
A new review explains how oxygen-starved retinal cells shift their metabolism, suffer mitochondrial failure, and die through regulated pathways that ...
A systematic review of 28 RNA sequencing studies shows biological pathway convergence in diabetic kidney disease despite substantial methodological heterogeneity.
A narrative review examines how sensory nerves, immune responses, and metabolic pathways intersect during ischemic stroke while urging rigorous validation ...
In a mouse and cell model of alcoholic cardiomyopathy, researchers found that reduced DBT gene activity promoted copper accumulation and ...
A new narrative review finds that antioxidant and mitochondria-targeted compounds show consistent benefits in Huntington's disease models but have repeatedly ...
Vanillic acid reduced paraquat-induced oxidative stress, mitochondrial depolarization, and acetylcholinesterase elevation in human neuroblastoma cells in a concentration-dependent laboratory study.
De novo designed microproteins, built computationally to bind toxic amyloid fibrils and restore mitochondrial function, are emerging as promising candidates ...
An editorial in World Journal of Pediatrics argues that butyrate, a short-chain fatty acid made by gut bacteria, is a ...
A narrative review of 50 longitudinal studies finds insulin-related nutrient sensing the most consistent biological hallmark linked to adverse muscle ...
A new mini-review proposes that durable senescence-like states in dorsal root ganglion sensory neurons may help explain why pain persists ...
