Engineered Bacteria Pill Cuts Bloodstream Infections in Stem Cell Transplant Patients
A phase 1 trial found that a pill of 16 selected beneficial bacteria was safe for stem cell transplant patients ...
Tag: Microbiome
Gut Microbes and Skin Disease: Why Probiotics Work for Some, Not Others
A new comparative review finds that probiotic effects in atopic dermatitis, acne, and psoriasis depend on disease biology, host factors, ...
Mussels and sea squirts harbor antimicrobial resistance genes in Mediterranean waters
A Mediterranean study found that farmed mussels and invasive ascidians harbor higher relative abundances of antimicrobial resistance genes and mobile ...
Gene Variants Tied to Vitamin D Reshape Gut Microbes in Postmenopausal Women
Variants in vitamin D metabolism genes VDR and NADSYN1 are associated with lower gut microbial diversity and altered bacterial abundance ...
Sweet Protein Brazzein Passes First Human Safety Trial as a Sugar Stand-In
A 21-day randomized controlled trial in 60 healthy adults found recombinant brazzein, a yeast-produced sweet protein, was well tolerated with ...
Deep learning tool Taxonova classifies microbiome species from short and long amplicon reads
Taxonova, a deep learning classifier, achieved high species-level accuracy across short- and long-read ribosomal amplicons in benchmark tests.
Review maps biotics as targeted microbial alternatives to antibiotics
A narrative review synthesizes evidence that probiotics, prebiotics, postbiotics, synbiotics and bacteriophages can reduce antibiotic-associated diarrhea risk and support antimicrobial ...
New bacterium found in infants’ noses hints at hidden airway microbiome diversity
Researchers have isolated a potentially novel bacterium, provisionally named Helcococcus ekapensis, from archived nasopharyngeal samples of South African infants and ...
Benchmark of 18 methods reveals limits of inferring microbial interactions from 16S count data
A benchmark of 18 co-occurrence network inference methods on synthetic 16S rDNA-seq data finds they perform reliably only under restricted, ...
New Bayesian Model Extracts Shared Microbial Signals Across Heterogeneous Studies
Researchers have introduced a statistical model designed to predict disease from microbiome data pooled across many studies, addressing a persistent ...
Endophytic actinomycete from Shiraia fungus triples hypocrellin A yield in co-culture
Researchers found that the endophytic actinomycete Streptomyces pseudogriseolus A6, isolated from Shiraia fruiting bodies, tripled fungal hypocrellin A production to ...
Genomics Goes Routine: From Model Labs to Honey Bees, Crops and Wild Populations
A new perspective argues that genomics has shifted from a specialized pursuit of well-funded labs to a routine tool now ...
Gut Microbiome Shifts Tied to Sarbecovirus Infection in Wild Cambodian Bats
Sarbecovirus-positive horseshoe bats in Cambodia show consistent gut microbiome restructuring and enriched Shigella and Escherichia, while diet shows no consistent ...
Tomato Plants Enlist Stress-Adapted Root Bacteria Under Salinity and Drought
A combined microbiome and cultivation study shows tomato plants selectively recruit stress-adapted rhizobacteria under salinity and drought, yielding 127 isolates ...
Blood, Stool and Urine Tests Could Track Gut Damage in Children With Celiac Disease
A mini review finds i-FABP and gluten immunogenic peptides the most promising emerging biomarkers for detecting intestinal damage and monitoring ...
Gut Microbes Send Chemical Signals That Shape Cancer and Metabolic Disease
A new review details how microbiome-derived metabolites such as short-chain fatty acids, secondary bile acids, and tryptophan derivatives regulate host ...
Ash leaf microbiomes share a core bacterial community shaped by climate and site
Across 12 forest sites in Germany, the bacterial communities living on the leaves of European ash trees share a small ...
Bile duct microbiome differs in structure between benign and malignant obstruction
Shotgun sequencing of bile from 48 patients found similar microbial diversity in benign and malignant bile duct obstruction, but different ...
Gut microbiome shifts in fibromyalgia track symptom severity, study finds
A study of 101 women found that gut microbiome differences in fibromyalgia were more pronounced when patients were stratified by ...
Bacteriophages Show Potential as Zinc Oxide Alternative Against Piglet Diarrhea
A multi-omics study found that bacteriophage treatment reduced diarrhea in ETEC K88-infected weaned piglets while shifting gut bacteria, bile secretion, ...
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