Tag: hypoxia

A study in Cancer & Metabolism reveals that SENP1 drives de novo cholesterol synthesis in prostate cancer by deSUMOylating SREBP2, ...

Single-cell RNA sequencing of human femoral head tissue reveals that alcohol-associated and glucocorticoid-associated osteonecrosis show distinct inflammatory, hypoxic and osteogenic ...

A new systematic review and three-level meta-analysis of ten studies in 216 athletes finds repeated-sprint training in hypoxia may modestly ...

Aged female mice show less hypoxia-induced blood-brain barrier disruption than males, with the microglial receptor CD11c identified as a key ...

Researchers found that circular RNA circUBR5 promotes ovarian cancer progression and angiogenesis in cell and animal models through a hypoxia-driven ...

Researchers developed a contrast-enhanced MRI radiogenomic surrogate reflecting a composite hypoxia, angiogenesis, and epithelial–mesenchymal transition transcriptional state that associates with ...

A new review explains how oxygen-starved retinal cells shift their metabolism, suffer mitochondrial failure, and die through regulated pathways that ...

A comprehensive review details the molecular and cellular mechanisms governing endometriotic lesion establishment, persistence, and progression, highlighting emerging mechanism-based therapeutic ...

Integrated single-nucleus and spatial transcriptomics of 43 choroid plexus tumours reveal ten tumour metaprograms that cluster by methylation subtype and ...

A mouse study finds that conditioning transplant recipients, not donors, under chronic hypoxia prolongs heart allograft survival through a HIF2-dependent ...

A single-cell and spatial atlas of 12 glioblastoma tumours shows that cancer cells progress through the same ordered sequence of ...

In a mouse cell-culture study, macrophage donor age rather than the age of circulating extracellular vesicles determined how well hypoxia-stressed ...

Clinical PET scans and laboratory experiments show that meibomian gland epithelial cells rely heavily on glycolysis and shift further toward ...

A new review finds that ozone therapy shows preclinical hints of antitumor activity in colorectal cancer models but lacks convincing ...

A new review in Cell Division details how colorectal cancer cells form their own blood-supply channels through vasculogenic mimicry, a ...

A review in Cellular Oncology proposes that tumor blood vessels actively regulate antitumor immunity through angiocrine, metabolic and structural mechanisms.

A new review synthesizes how hypoxia signaling and metabolic reprogramming shape tea's response to waterlogging, revealing a trade-off between flood ...

Researchers report that hypoxia activates a nuclear LOX-H1.5 decrotonylation axis that represses the DAG1 gene and promotes invasive progression in ...

A new cell-line study reports that silencing HIF-1α with siRNA synergizes with erlotinib to suppress proliferation, invasion and glycolysis in ...

A cell-culture study reports that prodigiosin reduced apoptosis and oxidative stress in BMSCs exposed to chemically induced hypoxia, with effects ...