An integrated single-cell transcriptomic atlas across development reveals progressive vascular niche maturation and demonstrates that blocking midkine enhances hematopoietic stem ...
A clinical study demonstrates that endosteal regulatory T cell reduction breaks down bone marrow immune privilege, driving severe long-term hematopoietic ...
A scientific review identifies clonal hematopoiesis as a measurable biological bridge connecting toxic environmental exposures to long-term health risks.
A review in Frontiers in Pediatrics summarizes how the fetal adaptive and innate immune systems develop across gestation and how ...
A one-hour exposure to activated protein C keeps human blood stem cells quiescent and improves their short-term serial engraftment in ...
A mouse study found that hematopoietic stem cells engrafted during active bone marrow regeneration showed superior long-term reconstitution compared with ...
A new perspective examines a recent study reporting that telomeres in mouse tails and leukocytes do not shorten with age, ...
Dominique Bonnet and Frederic Relaix join the Stem Cell Reports editorial team, adding expertise in hematopoietic malignancies, muscle stem-cell biology, ...
An AI tool called ChromAgeNet identifies aging in blood stem cells by detecting subtle age-related patterns in the 3D organization ...
Stanford researchers used a CRISPR screen in expanded blood stem cells to identify Elp1 as an essential regulator of myeloid ...
A new review in the Journal of Molecular Medicine explains how trained immunity, driven by epigenetic and metabolic reprogramming of ...
New research shows that the metabolic protein ANGPTL8 drives the aging of hematopoietic stem and progenitor cells by binding the ...
New research shows carboplatin drives the expansion of TP53-mutant blood clones far more strongly than PARP inhibitors, while inherited homologous ...
A new review details how the Runx1 and Gata2 transcription factors architect the epigenetic landscape of blood formation and how ...
Clonal haematopoiesis of indeterminate potential (CHIP) is emerging as a significant area of investigation within the context of age-related diseases, ...
A groundbreaking study from the University of Cambridge has unveiled the creation of three-dimensional embryo-like structures derived from human stem ...
