Tag: Exosomes

A study published in Epigenetics & Chromatin demonstrates that exosomes released by senescent fibroblasts accelerate skin photoaging by promoting a ...

Engineered exosome-liposome hybrid nanoparticles targeting CSF1R and PD-L1 stimulate macrophage phagocytosis across several brain cancer cell models in vitro, though ...

Researchers found that circular RNA circUBR5 promotes ovarian cancer progression and angiogenesis in cell and animal models through a hypoxia-driven ...

A scientific review outlines how extracellular vesicles mediate intercellular communication and carry overlapping molecular signals in aging tissues and cancer.

Researchers found that hypoxic pericytes release exosomal hexokinase 2 to promote retinal neovascularization through non-metabolic mTORC1 activation and ELK3 upregulation.

Researchers have identified that exosome MS4A8 promotes prostate cancer bone metastasis and osteolytic destruction by activating NF-κB and AKT pathways ...

A scientific review highlights how extracellular vesicles mediate inner ear damage and protection while offering potential biomarker and therapeutic applications ...

A review outlines how extracellular vesicles contribute to Sjögren's disease pathology while carrying molecular signatures that could serve as non-invasive ...

A rat study reports that intravenous human umbilical cord mesenchymal stem cells improved liver function, reduced steatosis and fibrosis, and ...

An in vitro study finds brain microvascular endothelial cells release extracellular vesicles in a polarized manner, with apical vesicles binding ...

A structured narrative review maps extracellular vesicle evidence in vascular cognitive impairment and dementia, finding therapeutic research still largely preclinical ...

Frontiers in Medicine has retracted a 2020 mouse study on exosomal miR-25 and fracture healing after image integrity concerns and ...

A new review describes how plant-derived extracellular vesicles carry stress-responsive proteins and RNAs between cells and may enable RNA-based crop ...

In a rat model of enterocutaneous fistula, gelatin sponges loaded with hypoxia-preconditioned exosomes reduced inflammation, shifted macrophages toward a reparative ...

A new mini-review details how hybrid and synthetic extracellular vesicle platforms are being engineered to overcome the low yield, heterogeneity, ...

Researchers report that the circular RNA circMAP2K4 promotes osteosarcoma progression by sponging miR-515-5p and derepressing G3BP2, and that it is ...

A new narrative review argues that mesenchymal stem cells, especially those from placental tissue, can heal chronic wounds and reverse ...

A new review outlines how engineered exosome nanocarriers could deliver drugs precisely to diseased heart tissue, while major manufacturing and ...

Human umbilical cord mesenchymal stem cell exosomes reduced kidney fibrosis in a preclinical model by delivering pVHL, which drives HIF-1α ...

Vestibular schwannoma-derived exosomes suppress GPX4 and disrupt iron homeostasis, triggering ferroptotic death of cochlear hair cells that a ferroptosis inhibitor ...