Tag: cancer therapy

BET inhibition suppresses STING expression at its promoter and enhancer regions, weakening the immune response triggered by PARP inhibitors.

A new review synthesizes how phosphorylation, ubiquitination, methylation, SUMOylation and O-GlcNAcylation form an interconnected network that controls the mitotic kinase ...

A new review examines how zinc oxide nanoparticles kill cancer cells selectively through reactive oxygen species, zinc ion imbalance and ...

A systematic review finds that nanoparticle and liposome delivery systems consistently improve resveratrol's stability and tumor uptake in preclinical models, ...

A new Nature Protocols article details how to design peptides that assemble inside living cells in response to glutathione or ...

A new review maps how biomaterials can exploit cholesterol metabolism in cancer while warning that most mechanistic claims remain unproven.

A review in Molecular Biology Reports examines how therapy-induced senescence and the SASP reshape the tumor immune microenvironment, and how ...

A new review argues that the molecular weight of hyaluronic acid, spanning oligosaccharides below 10 kilodaltons to chains above 6 ...

Research reveals that FDX1 downregulation in acute myeloid leukemia drives resistance to cuproptosis via the ROS/p53/ME1 axis, suggesting a new ...

A Molecular Cancer review redefines the MAD gene family as a unified HORMA-domain genome surveillance system linking spindle checkpoint control ...

St. Jude researchers show the DNA repair enzyme PARP1 evicts two histones near damage sites, forming hexasomes that recruit repair ...

A 2026 editorial synthesizes evidence associating dysbiosis with inflammation, genotoxicity, immune evasion, metabolism and cancer treatment outcomes while identifying variability, ...

A new review details how the NRF2 transcription factor shields cancer cells from iron-dependent ferroptotic death and how natural and ...

A comprehensive review in Cellular and Molecular Life Sciences maps how single ubiquitin marks on non-histone proteins regulate DNA repair, ...

Chemotherapy saves lives, but it can also leave chaos in its wake. One of the most widely used anticancer drugs, ...

A year of pharmacovigilance reports from Ho Chi Minh City shows that of 253 confirmed adverse reactions to anticancer drugs, ...

A new review in Pharmacia charts how magnetic nanoparticles, metal-organic frameworks, and ROS-responsive carriers are transforming targeted cancer therapy and ...

A new review links inherited variants in ABCB1, ABCC1, and ABCG2 drug transporter genes to differences in chemotherapy and targeted ...

A new review argues that plant-derived extracellular vesicles can both deliver and amplify the anticancer power of plant natural products, ...

A new review maps how two splice-variant proteins, CLDN18.2 and FGFR2b, became leading cancer drug targets, and why next-generation antibodies, ...