Plant Vesicles Turn Herbal Cancer Drugs Into Precision Weapons
A new review argues that plant-derived extracellular vesicles can both deliver and amplify the anticancer power of plant natural products, ...
Tag: cancer therapy
Splice Variants CLDN18.2 and FGFR2b Emerge as Prime Cancer Drug Targets
A new review maps how two splice-variant proteins, CLDN18.2 and FGFR2b, became leading cancer drug targets, and why next-generation antibodies, ...
Copper Overload Triggers a Distinct Form of Cell Death That Could Transform Cancer Therapy
A new review details how excess copper induces cuproptosis, a mitochondria-dependent form of cell death that cancer cells are uniquely ...
Ursolic Acid Emerges as a Multi-Target Natural Weapon Against Cancer
A new review in Molecular Biology Reports maps how the apple-skin compound ursolic acid switches on cancer cell death, silences ...
Hidden RNA Molecule Drives Ovarian Cancer by Stabilizing Two Key Oncoproteins
A long non-coding RNA called RBMS3-AS3 has emerged as a powerful molecular accomplice in ovarian cancer, according to a new ...
Molecular Hydrogen Emerges as a Versatile Adjuvant in Cancer Therapy
A new review in Frontiers in Chemical Biology maps how molecular hydrogen reprograms oncogenic signaling, epigenetics, mitochondrial stress, and antitumor ...
Copper Nanoparticles Emerge as Multifunctional Weapons in Drug Delivery and Cancer Therapy
A comprehensive review highlights how copper nanoparticles combine drug delivery, targeted tumor therapy, and the newly discovered cell death pathway ...
Yeast Genome Shuffling Spawns New Chimeric Poxviruses With Cancer-Killing Potential
Researchers have developed a yeast-based genome shuffling platform that generates infectious chimeric poxviruses from multiple parental species, yielding clones with ...
Hidden Molecular Shield Lets Lung Cancer Cells Dodge Copper-Driven Cell Death
Researchers have mapped a USP11-IGF2BP2-ATOX1 molecular axis that shields non-small cell lung cancer cells from copper-induced cuproptosis, revealing new drug ...
Ribosomal RNA Tag and a Detox Enzyme Form a Deadly Cancer Survival Circuit
A new review describes how the RNA methyltransferase METTL5 and the detox enzyme MGST1 form a signaling axis that helps ...
Deuterium swap turns one molecule into a brighter, tougher cancer fighter
Researchers at Shenzhen University show that replacing hydrogen with deuterium in a near-infrared fluorescent molecule simultaneously improves imaging brightness, therapeutic ...
TEAD transcription factors emerge as a new frontier in cancer therapy
A new review in Molecular Cancer details how the TEAD family of transcription factors drives cancer, the drugs now targeting ...
First-in-class NVL inhibitors starve tumors by blocking ribosome assembly
Researchers have developed the first selective inhibitors of the NVL ATPase, blocking 60S ribosomal subunit assembly to activate p53 and ...
One Cancer Gene, Two Fates: Study Shows Senescent Cells Split Into Tumor Blockers and Tumor Seeds
An NYU Abu Dhabi study in EMBO Reports shows that a single cancer-causing gene drives liver cells into distinct senescent ...
AI Reads Live Cell Videos to Predict Cancer Cell Fates Before They Happen
A Transformer deep learning model predicts cancer cell fates directly from live-cell videos with high accuracy up to eight hours ...
Pencil-Tip Robots Ride the Bloodstream to Deliver Drugs to a Beating Heart
Johns Hopkins engineers have developed wireless, magnetically steered millirobots that travel through the bloodstream to dock on a beating heart ...
Beyond the On-Off Switch: Chemical Tags on KRAS Reshape Cancer Drug Design
A new review in Advanced Cancer Research details how post-translational modifications regulate KRAS localization, activity, stability, and degradation, opening fresh ...
Molecular Tags of Cell Death: How E3 Ubiquitin Ligases Steer Necroptosis in Cancer
A new review explains how E3 ubiquitin ligases attach molecular tags to the necroptosis machinery, shaping both cancer development and ...
Low Oxygen Turns Inflammatory Switch That Drives Oral Cancer Growth
New research in the British Journal of Cancer shows that oxygen-starved oral cancer cells activate an HMGB1-driven NLRP3 inflammasome pathway ...
Gallic Acid Shrinks Tumors in Mice While Sparing Blood Cells, Study Finds
A new preclinical study shows that orally delivered gallic acid significantly inhibited sarcoma tumor growth in mice by suppressing proliferation, ...
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