Researchers found that mechanosensitive ion channel PIEZO1 regulates endometrial receptivity during embryo implantation through a calcium-dependent NFATc2 transcriptional pathway, with ...
Proteomic analysis of aging macaques reveals region-specific molecular changes following chronic GCPII inhibition, highlighting potential therapeutic targets for sporadic Alzheimer's ...
Researchers have demonstrated that domestic cat oocytes express functional TRPV3 ion channels whose distinct structural features explain altered pharmacological activation ...
Cancer-associated fibroblasts deliver blood-borne cholesterol to pancreatic cancer cells and suppress T cell function through ANO6-dependent trogocytosis, a contact-based membrane ...
A new study identifies Tollip as a conserved negative regulator of ESCRT-III-mediated plasma membrane repair, showing that the protein balances ...
A new review in Plant Cell Reports synthesizes how the non-protein amino acid GABA links plant metabolism, development, and stress ...
A new narrative review details how hyperglycemia, Schwann cell dysfunction, and disrupted calcium and iron balance impair peripheral nerve regeneration ...
Transcriptome sequencing of ventilated rat diaphragms identifies MAPK, PI3K-Akt, and Calcium signaling as inflammation-linked pathways associated with muscle fiber atrophy ...
New research in Cell Division shows that Bcl-2 overexpression promotes survival of cutaneous squamous cell carcinoma cells by altering mitochondria-associated ...
A systematic comparison shows four neuroscience simulation tools produce consistent calcium reaction–diffusion results, while astrocyte branchlet geometry strongly shapes signaling.
Ultra-high-speed imaging shows that ultrasound-vaporized bubbles permeabilize fibroblasts within about one bubble radius in fibrin gels, while calcium responses reach ...
In a rat model of pulmonary arterial hypertension, surgically cutting the cervical sympathetic trunk lowered lung pressures and reshaped transcription ...
Researchers report that SYNJ2BP rises in atrophied human and mouse supraspinatus muscle and that local knockdown attenuated muscle wasting in ...
A mouse study identifies the mechanosensitive channel Piezo1 in ST36 muscle cells as the trigger that converts acupuncture's mechanical force ...
A new study reports that the ubiquitin ligase substrate receptor DCAF13 promotes hepatocellular carcinoma progression by targeting RCAN1.4 for degradation ...
A new study in mice and cardiomyocytes shows that TRPM7 promotes ischemia-reperfusion heart injury through a CaMKII/DDX3X/NLRP3 pathway that drives ...
A new mouse and cell study finds that Toxoplasma gondii infection disrupts a Trem2-dependent protective signaling pathway in macrophages at ...
A new review synthesizes how the calcium sensor STIM1 and store-operated calcium entry regulate physiology across tissues and contribute to ...
Researchers used optogenetic melanopsin stimulation in HeLa cells to show that the timing pattern of light-evoked calcium signaling selectively shapes ...
A pH- and ROS-responsive hydrogel carrying CRISPR-Cas9 silenced the TRPV4 calcium channel in rat discs, restoring autophagic flux and slowing ...
