Cancer

An animal study by City of Hope researchers shows that modular CAR T cells can accept engineered adaptors after treatment,...

A new university spin-out is developing steroid-signature tests for adrenal cancer and metabolic ovarian syndrome, with regulatory certification and clinical...

An observational study found hidden immune activity and a distinctive gut environment in bowel disease associated with PSC, offering a...

Binghamton University researchers received SUNY seed funding to develop an AI pathology model and an amino-acid-based nanoparticle platform for delivering...

In preclinical castration-resistant prostate cancer models, combining B7-H3 blockade with the MEK inhibitor trametinib overcame compensatory immune suppression and structural...

The 35,878-person PATHFINDER 2 trial found 6.5-fold more cancers when Galleri was added to routine screening, but it did not...

A five-year National Cancer Institute grant will support efforts to identify biomarkers that predict response and relapse in older adults...

A prospective study found that a multicancer blood test detected signals across 17 cancer types with 99.64% specificity, but randomized...

A randomized trial of 443 older adults in cancer rehabilitation found fewer inappropriate prescriptions and less medication overuse and underuse...

A systematic analysis found 485 breast cancer-relevant chemicals in pesticide formulations, including 145 registered active ingredients and many poorly tested...

A JAMA Surgery modeling study estimates a substantial ovarian cancer risk among BRCA1 carriers who defer bilateral salpingo-oophorectomy until age...

A preclinical study reports that cannabidiol selectively impaired viability, migration, invasion, and clonogenic survival of cisplatin-resistant HPV-negative head and neck...

An analysis of 219 epithelial ovarian cancers found that HER2 protein expression and gene amplification varied by tumor subtype, while...

A retrospective cohort of 331 initially diagnosed patients with HCC and Vp3/4 portal vein tumor thrombosis found a 61.3% objective...

A University of Michigan study of two independent cohorts found that patients with lobular metastatic breast cancer are far more...

A retrospective cohort of 269 breast cancer patients found that GLP-1 receptor agonists produced significant but markedly attenuated weight loss...

A cell-based study reports that lipopolysaccharide boosts gallbladder cancer cell migration and invasion by potentiating NF-κB-driven CXCR4 expression, an axis...

A tissue microarray study of 347 clear cell renal cell carcinomas finds that p16 expression in intratumoral blood vessels, rather...

A Molecular Cancer review redefines the MAD gene family as a unified HORMA-domain genome surveillance system linking spindle checkpoint control...

A Nature Reviews Cancer review surveys the statistical and computational methods that reconstruct tumour evolutionary histories from single-cell sequencing data...