Biology
Gut microbiome imbalance expands inflammatory dendritic cells, triggering early autoimmunity
Long before lupus announces itself with swollen joints and damaged kidneys, long before type 1 diabetes destroys enough insulin-producing cells...
Human TOM and TIM22 complexes join forces to import mitochondrial carriers
You are the science news desk of a major English-language science magazine. Complete the task immediately. Never ask the reader...
Mol2Image turns drug molecular descriptors into images to predict interactions
In a development that could reshape how the pharmaceutical world screens for hazardous drug combinations, researchers have unveiled Mol2Image, a...
Disrupted TDP-43/RILP pathway impairs cellular cleanup and stress granule balance
Inside every neuron, a molecular housekeeping system works around the clock: it engulfs damaged proteins and worn-out organelles in double-membrane...
Rural groundwater viruses shape microbial communities, metagenomic study reveals
Deep beneath three village hand pumps in Egypt’s Nile Delta, an unseen empire of predators is thriving, and almost none...
Genome study reveals genetic basis of cotton fiber color and whiteness
Every year, the textile industry drenches billions of kilograms of cotton in synthetic dyes, a process that consumes enormous volumes...
Ginsenosides Show Promise Against Neurodegenerative Diseases by Blocking Ferroptosis
Ginseng has sat at the intersection of folklore and pharmacology for more than two thousand years, prized across East Asia...
Immune gene diversity mapped in critically endangered disease-prone freshwater turtle
In 2015, a virus swept through a single Australian river and erased ninety percent of the turtles living in it....
Marine chitinase BtChi attacks Candida cell walls, releasing antifungal chitooligosaccharides
The ocean has spent hundreds of millions of years perfecting the chemistry of tearing chitin apart, and scientists in India...
Harnessing WRKY Genes to Boost Potato Stress Tolerance and Yield
The potato has earned its place as one of humanity’s most dependable staples: calorie-dense, fast-maturing and adaptable enough to help...
How SHH-Wnt crosstalk, DNA methylation, and miRNAs drive uterine fibroids
Uterine fibroids may be the most familiar enemy most people have never heard of. These benign tumors of the muscular...
Two Cuckoo Lineages Parasitize the Same Daurian Redstart Nest
On a June morning in 2024, in a village tucked between arable fields and secondary forest in northeastern China, field...
Genome-Wide Scan Reveals Type VI Secretion Systems Across Morganella Species
In a finding that rewrites what scientists thought they knew about one of medicine’s most overlooked gut bacteria, researchers have...
GWAS-informed ensembles boost genomic prediction of vitamin A carotenoids in cassava
Cassava is a lifeline for millions of people across sub-Saharan Africa, but it is an imperfect lifeline. The starchy roots...
Magnesium Emerges as Key Regulator of Mitochondria, Metabolism, and Aging
Magnesium has spent most of its scientific life backstage — the unglamorous electrolyte that keeps cellular housekeeping running while genes,...
GNG10 Drives Colorectal Cancer Through Non-Canonical Wnt Signaling
Hidden Engine of Colorectal Cancer Uncovered: A Single Signalling Protein Fuels Tumour Growth Through an Unconventional Wnt Route Scientists have...
Novel TCF4 Splicing Variant Linked to Pitt-Hopkins Syndrome
A Routine Pregnancy Scan Just Exposed the Earliest Warning Sign Yet of a Devastating Genetic Syndrome For decades, doctors have...
Metanephrine-Secreting Dog Adrenal Cancer Mimicked Pheochromocytoma, Case Shows
In a finding that blurs one of the sharpest diagnostic lines in endocrine medicine, veterinarians in South Korea have documented...
Ticks and Blood Parasites Strike Captive African Rock Python in Nigeria
A 9-Foot Python, 754 Ticks, and Hidden Blood Parasites: Nigerian Veterinarians Rescue a Giant Snake on the Brink When a...
Malt and hop compounds strengthen skin antioxidant defenses against psoriasis inflammation
Beer’s Building Blocks, Refined: Malt and Hop Polyphenols Show Promise Against Psoriasis in Preclinical Tests In a result that reads...