Tag: tumor microenvironment

A narrative review identifies prostate cancer stem-like cells as plausible contributors to treatment persistence and relapse while concluding that most ...

A 2026 review proposes that bacteriophage-derived delivery, barrier-breaching and immune-stimulation features could help oncolytic viruses penetrate cold tumors and stimulate ...

A public-data multi-omic study found a reproducible epithelial program shared by pancreatic ductal adenocarcinoma and ischemic stroke, while related myeloid ...

A 2026 conceptual paper proposes that cancer can emerge from coupled changes in cellular energy, environment, mechanics and information, while ...

A retrospective Chinese cohort study found that perineural invasion in resected colorectal cancer was independently associated with distant metastasis and ...

A 2026 review finds that several non-coding RNAs are associated with tumor-associated macrophage states, pathways linked to colorectal cancer progression, ...

A 2026 review summarizes recurrent molecular alterations, immune suppression, multimodal imaging and current treatment strategies for primary cardiac angiosarcoma, a ...

A study combining clinical-data analysis, functional cell experiments and single-cell transcriptomics linked the METTL1–NSUN1 axis to malignant progression and immune-microenvironment ...

An analysis of 81 Ethiopian breast cancer tissue samples associated higher immune-cell and PD-L1 measures with non-luminal subtypes and grade ...

A controlled syngeneic mouse study found that intracranial A20 B-cell lymphoma had stronger T-cell exhaustion, regulatory-cell expansion and dendritic-cell immunoregulation ...

A 2026 review proposes modernizing the murine Ehrlich carcinoma model with multi-omics, single-cell profiling, CRISPR experiments and RISC-centered analysis while ...

An in vitro 3D cell-line study found that adding LX-2 hepatic stellate cells to HepG2 hepatocellular carcinoma spheroids was associated ...

A multi-omics study in murine cervical cancer models found that tumor-conditioned MDSCs underwent sphingolipid metabolic changes centered on a KNG1–sphingosine ...

A label-free dual-channel terahertz biosensor separated cultured colorectal cancer fibroblast subtypes through characteristic resonance and group-delay shifts, but the approach ...

A nine-patient phase I trial found that TIGIT-disrupted NK510 could be combined with PD-1 blockade without observed dose-limiting toxicities in ...

A 2026 commentary proposes that metabolic plasticity, stromal reprogramming and immune-metabolic competition create an adaptive tumor ecosystem that can promote ...

A 2026 systematic review judges arsenic a causal bladder-cancer risk factor, cadmium likely causal, chromium probable and lead possible while ...

In vitro experiments found that exosomes from dimethyl-itaconate-treated macrophages increased EMT-associated changes, migration, and invasion in MCF-7 breast cancer cells ...

A 2026 review finds that epigenetic changes sustain PI3K/AKT signaling in hepatocellular carcinoma, while experimental evidence indicates activated signaling can ...

A prostate-cancer study found that extracellular vesicles carrying miR-302/367 microRNAs can reprogram macrophages toward an M2-like immunoregulatory state.