Tag: tumor-associated macrophages

A new narrative review in Frontiers in Oncology details how T cells, macrophages, neutrophils, B cells, NK cells, and dendritic ...

A computational study identified KRT14 and MMP10 as macrophage-associated candidate biomarkers of chemoradiotherapy response in esophageal squamous cell carcinoma.

A preclinical study reports that ginseng-derived ginsenoside Rg3 binds Glut1 on tumor-associated macrophages, reprograms their metabolism, and enhances anti-PD-1 therapy ...

A new review details how metabolically reprogrammed cancer-associated fibroblasts build immune-excluded and immunosuppressive tumor niches that undermine checkpoint blockade, and ...

A new cell-culture study reports that an EGFR-IL-8 signaling loop between liver cancer cells and macrophages sustains lenvatinib resistance in ...

A preclinical study reports that formononetin from Jianpi Tongluo Formula suppresses colorectal cancer progression by inhibiting M2 tumor-associated macrophage polarization ...

Single-cell and multi-omics analyses of hepatocellular carcinoma point to IL-1β-positive macrophages and IL-1R1-positive inflammatory fibroblasts as putative drivers of a ...

A new narrative review finds that the clinical meaning of immune infiltration in bladder cancer depends on cell localization, functional ...

Researchers have identified a rare CD4-lineage progenitor in adult mouse bone marrow that generates macrophages, neutrophils and erythroid cells independently ...

Single-cell sequencing and mouse experiments show that PTN-positive glioblastoma cells recruit anti-inflammatory macrophages through a PTN-NCL interaction, creating the immune ...

A 2026 review finds that several non-coding RNAs are associated with tumor-associated macrophage states, pathways linked to colorectal cancer progression, ...

A 2026 narrative review finds that most myeloid-directed cancer programs show target activity without proving immune conversion and proposes a ...

An analysis of 81 Ethiopian breast cancer tissue samples associated higher immune-cell and PD-L1 measures with non-luminal subtypes and grade ...

A multi-omics study links the antiviral protein RSAD2 to CXCL1–CXCR1/2 signaling that recruits macrophages and drives endometrial cancer progression.

Japanese researchers have built a microfluidic chip that uses human macrophages as living biological transducers, converting unknown cancer-cell-derived signals into ...

New research shows that high-dose vitamin C activates the JAK2-STAT1 pathway to drive macrophages toward an anti-tumor M1 state, enhancing ...

A new review in Molecular Cancer argues that microbes living inside tumors dynamically reprogram immunity and can determine whether patients ...

A new study shows that the macrophage enzyme MMP14 generates soluble semaphorin 4D, a signal that builds an immunosuppressive tumor ...

A new review in iMetaMed reveals how cysteine peptidases such as cathepsins B, S, L, and X control antigen presentation ...

New MSK studies reveal that immune cells secretly feed triple-negative breast cancer, a CXCR2 blocker sensitizes leptomeningeal metastases to radiation, ...