Two SOD1 Aggregate Strains Differ in How Fast ALS-Like Disease Spreads to the CNS
In SOD1G85R mice, sciatic nerve inoculation with two distinct SOD1 aggregate strains transmitted templated aggregation to the CNS, with strain ...
Tag: templated aggregation
SOD1 Aggregates Injected into Brain Fluid Trigger ALS in Mice
Injecting two strains of misfolded human SOD1 aggregates into the cerebrospinal fluid of transgenic mice triggered prion-like aggregation and fatal ...
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