Tag: pyroptosis

A multi-stage Mendelian randomization study suggests that the gut bacterium Gordonibacter pamelaeae is associated with a reduced risk of osteoarthritis, ...

A new study shows that hESC-MSC-EVs reduce brain injury after cardiac arrest by inhibiting cGAS/STING-mediated neuronal pyroptosis.

A new study in Cellular Oncology shows that cucurbitacin I induces pyroptosis in cervical cancer cells via a specific molecular ...

A review in Pathology and Oncology Research details how cancer cells develop composite resistance to multiple regulated cell death pathways ...

A screening study reveals that cyclofenil inhibits NLRP3 inflammasome assembly, preventing IL-1β secretion and pyroptosis independently of estrogen receptor pathways.

A review in Cardiovascular Diabetology indicates that diabetic cardiomyopathy develops through an interconnected network of regulated cell death programs rather ...

In a retrospective cohort of critically ill sepsis patients, circulating cell-death signatures and admission lactate levels tracked kidney injury severity ...

A new review in Cell Communication and Signaling examines how three forms of regulated cell death interact in pancreatic ductal ...

Researchers have identified a specific mechanism by which the porcine reproductive and respiratory syndrome virus (PRRSV) evades a critical host ...

A critical review finds direct circRNA–NLRP3 evidence in reproduction limited to four placental, trophoblast, or granulosa-cell models, with no functional ...

A new study reports that methylene blue protects mice from septic shock by upregulating FASN in neutrophils, which suppresses NLRP3-mediated ...

A new study reports that TROP2 suppresses pyroptosis through the PI3K/AKT pathway, promoting hypopharyngeal squamous cell carcinoma progression.

A new review maps how metabolic reprogramming controls gasdermin-mediated pyroptosis in tumors and outlines a four-level evidence framework for precision ...

An editorial in World Journal of Pediatrics argues that butyrate, a short-chain fatty acid made by gut bacteria, is a ...

In a lithium-pilocarpine rat model of status epilepticus, hippocampal GSDMD knockdown reduced pyroptosis and ferroptosis markers, improved neuronal survival, and ...

A new review distinguishes a myeloid gasdermin D inflammatory relay from photoreceptor-intrinsic gasdermin E lysis in retinal degeneration and grades ...

A mouse study finds that inhibiting the NLRP3 inflammasome specifically in microglia reduces hippocampal neuroinflammation and reverses cognitive deficits after ...

A new study finds that elevated serum miR-424-3p is an independent prognostic marker for colorectal cancer, linked to suppression of ...

A new Biology Direct study shows that periplocin suppresses osteosarcoma cell proliferation and tumor growth in preclinical models by inducing ...

A three-component nanoparticle that consumes tumor glucose and triggers pyroptosis and cuproptosis suppressed liver cancer growth and established immune memory ...