Prostate Cancer Study Links PSA Density and Nerve Invasion to Gleason Upgrading
A retrospective cohort study of 124 men with biopsy Gleason 6 prostate cancer found that elevated PSA density and perineural ...
Tag: Prostate Cancer
Traditional Chinese Medicine Compounds Trigger Cancer Cell Ferroptosis via TP53
Researchers report that ursolic acid and Anhydroicaritin, key components of the traditional formula Fuzheng Yiai, bind and upregulate TP53 to ...
Prostate Cancer Detection Rose After MRI Arrived, But a Single-Centre Study Says the Reason Stays Unclear
A retrospective comparison of 384 men at one Chinese hospital found higher age- and PSA-standardised prostate cancer detection in 2022 ...
Four-Gene Signature Predicts Prostate Cancer Recurrence and Flags SPAG5 as Drug Target
A four-gene transcriptomic signature stratifies prostate cancer patients by biochemical recurrence risk and identifies SPAG5 as a targetable oncogene.
Threshold-Based Segmentation Outperforms Gradient Methods for Tracking Tumour Volume on Lu-177 PSMA SPECT/CT
A study of 24 post-therapy SPECT/CT scans found threshold-based segmentation far more reproducible than gradient-based methods for measuring tumour volume ...
New PSMA-Targeted Radioligand Shows Stronger Tumor Uptake Than Lu-PSMA-617 in Mice
In preclinical LNCaP mouse models, the novel PSMA-targeted radioligand Lu-M3-12 showed higher tumor uptake and a better tumor-to-kidney ratio than ...
Computational Predictions Fail to Match Measured Activity at Prostate Cancer Risk Variants
A re-analysis of prostate cancer reporter assay data shows computational annotations poorly predict measured regulatory activity, while ovarian risk variant ...
PET Tumour Metrics Reflect Radiation Absorbed Dose in Radiopharmaceutical Therapy
A letter in EJNMMI Reports argues that tumour SUVmean and volume act as surrogates for the radiation absorbed dose that ...
Experimental Compound NAF19 Blocks Key Growth Signals in Prostate Cancer Cells
A new laboratory study reports that the arylpiperazine derivative NAF19 suppresses proliferation, migration, invasion and survival signaling in five prostate ...
Public cancer investment linked to better survival at Uganda’s leading cancer centre
A five-year study of 12,438 patients at the Uganda Cancer Institute finds that residence outside Kampala, informal employment, and HIV ...
Higher Preoperative Testosterone Linked to Faster Urinary Continence Recovery After Prostate Surgery
A retrospective study of 482 prostate cancer patients found that higher preoperative testosterone was associated with faster urinary continence recovery, ...
PET Scans Before Therapy Predict Radiation Doses in Prostate Cancer Treatment
A study of 31 patients shows pre-therapy PET metrics can predict absorbed radiation dose to tumors and organs during prostate ...
PSMA PET-guided robotic transgluteal biopsy outperforms TRUS fusion biopsy in Indian cohort
A prospective Indian study found that PSMA PET/CT-guided robotic transgluteal biopsy detected more clinically significant prostate cancer and caused fewer ...
Recalibrating Polygenic Risk Scores to Local Data Sharpens Disease Risk Prediction
A new framework recalibrates published polygenic risk scores to local biobank data, improving risk prediction for coronary artery disease, breast ...
Plasma GDF15 Shows Diagnostic Potential in Biopsy-Indicated Prostate Cancer Cohort
A biopsy-indicated cohort study found plasma GDF15 achieved an AUC of 0.805 for prostate cancer detection, and a nomogram combining ...
Secure WhatsApp recruitment system built to reach Black men in prostate cancer research
Cardiff University researchers describe a secure, community-led WhatsApp recruitment system with layered verification and encryption for prostate cancer research with ...
Decades of AI in Prostate Cancer Show Technical Gains but Clinical Utility Remains Elusive
A review of three decades of artificial intelligence in prostate cancer demonstrates that while technical performance has advanced significantly, definitive ...
Cancer gap widens between people with and without type 2 diabetes
A nationwide Danish study presented at the EASD annual meeting found cancer incidence was 12% higher in men and 22% ...
Validated HPLC and TLC methods confirm purity of zirconium-89 PSMA tracer for clinical use
Researchers validated HPLC and TLC analytical methods for measuring the radiochemical purity of the zirconium-89 labelled PSMA-I&T radiotracer ahead of ...
Experts in Singapore and Malaysia Issue Consensus on Heart Risks of Prostate Cancer Therapy
A 12-member expert panel from Singapore and Malaysia has issued 12 consensus statements on assessing, monitoring and managing the cardiometabolic ...
