Extracellular vesicles may reshape prostate cancer metabolism and its microenvironment
A new review describes how prostate cancer reverses its specialized citrate-producing metabolism and how extracellular vesicles may transfer metabolic signals ...
Tag: Prostate Cancer
PSMA PET MRI Spots Prostate Cancer Recurrence in a Quarter of Men Right at the Start of Biochemical Relapse
A prospective study of 24 men found that 18F-Flotufolastat PSMA PET MRI detected recurrent prostate cancer in 25 percent of ...
AI and molecular studies converge to decode cancer complexity in new research collection
A new Frontiers in Oncology editorial surveys thirteen studies using artificial intelligence and molecular data to advance cancer diagnosis, prognosis ...
Three genes tied to lactylation and lactate metabolism may flag prostate cancer recurrence risk
An integrated sequencing analysis identified MKI67, MIPEP and CCNA2 as candidate prognostic biomarkers for biochemical recurrence risk in prostate cancer.
Case report links relugolix to severe polyarthritis with myositis-like features in prostate cancer patient
A published case report describes a prostate cancer patient who developed polyarthritis with myositis-like features, fever and systemic inflammation after ...
New risk model may help spare nearly half of men with PI-RADS 3 prostate lesions from immediate biopsy
A retrospective study of 919 men proposes a pre-stratified risk model that could defer biopsy in nearly half of patients ...
Most Swedish cancer survivors use primary care, but satisfaction varies widely between groups
A Swedish cross-sectional survey of people with breast, prostate, lung, or colorectal cancer found that almost all had used primary ...
Shorter PET/CT scans may miss prostate cancer recurrence signs in some patients
A retrospective study of 200 patients found that shortened 68Ga-PSMA PET/CT protocols miss tumor manifestations in a minority of patients ...
Long Noncoding RNA SNHG4 Emerges as a Player Across Multiple Human Cancers
A new review consolidates reported expression patterns, mechanisms, and clinical potential of the long noncoding RNA SNHG4 across six cancer ...
Prostate Tumors in Hispanic American Men Show Distinct Molecular and Immune Features
A retrospective study of 83 men with metastatic hormone-sensitive prostate cancer found that Hispanic American patients presented with more advanced ...
Shorter Radiation Courses Become Standard Care for Localized Prostate Cancer in New Guideline
A new ASTRO clinical guideline recommends moderately shortened radiation schedules for all risk groups of localized prostate cancer and establishes ...
ECHS1 Linked to Hypoxia-Driven PGK1 Crotonylation in Prostate Cancer Models
A new study links the metabolic enzyme ECHS1 to hypoxia-responsive PGK1 crotonylation and malignant phenotypes in prostate cancer cell and ...
Data-Driven Gating Boosts PSMA PET Quantification of Prostate Cancer Metastases
A retrospective study reports that hardware-free data-driven gating significantly increased SUV measurements, improved contrast-to-noise ratio and reduced image noise compared ...
Long-Term Trial Data Show Triplet Therapy Extends Survival in Metastatic Prostate Cancer
Long-term PEACE-1 trial results show that adding abiraterone to ADT and docetaxel reduced the risk of death by 32 percent ...
Alpha-Emitting Prostate Cancer Therapy 212Pb-ADVC001 Well Tolerated in First-in-Human Trial
In the first-in-human TheraPb phase 1 trial, the alpha-emitting radiopharmaceutical 212Pb-ADVC001 was well tolerated at doses of 60–200 MBq with ...
Fewer low-risk prostate cancers treated as active surveillance becomes the norm
An analysis of United States registry and health system data shows low-risk prostate cancer is being diagnosed less often and, ...
Perioperative apalutamide cuts metastasis and death risk in high-risk prostate cancer substudy
A phase 3 PROTEUS substudy published in European Urology reports that perioperative apalutamide plus hormone therapy around radical prostatectomy improved ...
Kidney Radiation Doses Stay Low in Most Men After PSMA Therapy
A retrospective analysis of 127 patients found that only 5 percent-level few exceeded 20 Gy cumulative kidney dose after lutetium-177 ...
Himalayan Plant Compounds Show Dual Action Against Lung and Prostate Cancer Cells
Podophyllotoxin and atisine from Himalayan medicinal plants showed potent cytotoxicity against lung and prostate cancer cells and favourable predicted binding ...
Rising Cancer Stemness Drives Prostate Cancer Progression and Treatment Resistance
A large integrated transcriptomic study shows that rising cancer stemness tracks prostate cancer progression, lineage plasticity, therapy resistance, and poor ...
