Rising Cancer Stemness Drives Prostate Cancer Progression and Treatment Resistance
A large integrated transcriptomic study shows that rising cancer stemness tracks prostate cancer progression, lineage plasticity, therapy resistance, and poor ...
Tag: Prostate Cancer
Rare prostate cancer subtypes demand better detection and dedicated trials
A new review finds that rare prostate cancer histologies, which make up less than 5% of cases, are aggressive, often ...
Zoledronic Acid Outcomes Reported in Ivorian Prostate Cancer Cohort
A retrospective cohort of 144 men in Côte d'Ivoire found that 20.8 percent of patients with metastatic castration-resistant prostate cancer ...
WDR4 Gene Variant Linked to Prostate Cancer Risk in Genetic Study
A genetic variant in the RNA-modifying gene WDR4 has been associated with prostate cancer susceptibility in a two-stage genetic association ...
PSMA-PET/CT detected 91% of clinically significant prostate cancers in biopsy study
A retrospective analysis of 194 patients found that PSMA-PET/CT identified 91% of clinically significant prostate cancers and had a high ...
Blood DNA biomarkers track progression during prostate cancer radioligand therapy
A prospective observational study linked circulating tumor DNA fraction and copy-number burden with progression and survival in 78 patients receiving ...
StereoBed trial to compare radiotherapy schedules after prostate surgery
The multicenter StereoBed trial will randomize 284 patients to compare five-fraction stereotactic radiotherapy with standard schedules after prostatectomy, with two-year ...
Alliance webinar showcases latest cancer research from 2026 ASCO Meeting
A free October 1, 2026 webinar will discuss four Alliance clinical-trial findings from the 2026 ASCO Annual Meeting in breast, ...
Blood proteins linked to prostate cancer risk over decade before diagnosis
A prospective EPIC-based study found blood-protein associations with prostate cancer more than 15 years before diagnosis, including markers linked to ...
B7-H3 blockade and MEK inhibition overcome immune defenses in prostate cancer models
In preclinical castration-resistant prostate cancer models, combining B7-H3 blockade with the MEK inhibitor trametinib overcame compensatory immune suppression and structural ...
TCGA study links coagulation-associated lncRNAs to prostate cancer prognosis
A TCGA-based prostate cancer study developed a coagulation-associated lncRNA prognostic signature, found distinct immune-related features in high-risk patients, and showed ...
AI platform identifies synergistic drug combination for resistant prostate cancer
A UCLA artificial intelligence platform paired with three-dimensional tumor testing identified berberine and enzalutamide as a synergistic combination in four ...
Erianin curbs prostate cancer growth in mice and dampens STAT3 signaling
Preclinical experiments found that erianin reduced prostate cancer cell activity and mouse tumor growth while lowering phosphorylation of the STAT3 ...
HPV E6/E7 proteins linked to aggressive features in Sudanese prostate cancer
Immunohistochemical staining was positive in 48% of the 50 prostate cancer specimens and 18% of the 50 benign controls, a ...
Meta-analysis links serum TK1 to prostate cancer and tumor grade
A systematic review and meta-analysis of eight studies found elevated serum TK1 in prostate cancer and an association with higher ...
Urinary bacterium revealed as unexpected testosterone maker in lab study
A laboratory study found that the urinary bacterium Actinobaculum massiliense can convert DHEA into testosterone, and molecular simulations from Auburn ...
HLTF Linked to Prostate Cancer Cell Growth in Laboratory Study
A computational and laboratory study found that reducing HLTF diminished prostate cancer cell proliferation and suggested regulation of ZBP1-PANoptosome assembly ...
Breast Cancer Drug Lapatinib Shows Modest Boost to Ultrasound Therapy in Prostate Cancer Cells
A laboratory study finds that the approved kinase inhibitor lapatinib can improve retention of a nanoparticle sonosensitizer in hypoxic prostate ...
Largest real-world cohort confirms PSMA radiopharmaceutical therapy works in routine prostate cancer care
A French early-access program of 3,709 patients with metastatic castration-resistant prostate cancer found that 177Lu-PSMA-617 produced efficacy and safety outcomes ...
Immune Gene Signatures Converge on FLT3 in Prostate Cancer Analysis
A combined bulk and single-cell transcriptomic study identifies FLT3 and AIM2 among immune-associated genes in prostate cancer, while cell-line knockdown ...
