Brazilian cancer biobank targets precision prevention for diverse population
A Hospital de Amor biobank has collected nearly 40,000 blood samples from more than 4,000 Brazilians to develop cancer risk ...
Tag: Precision Medicine
Gut microbiome may influence variable responses to MASH therapies
A review finds that microbial metabolites may influence variable responses to MASH therapies, but direct clinical evidence linking gut microbial ...
Large Language Models Could Help Detect Pharmacogenomic Phenoconversion
A 2026 perspective proposes that large language models could integrate genetic and clinical records to identify possible pharmacogenomic phenoconversion, while ...
Molecular mechanisms of programmed cell death in aortic dissection and advances in clinical translation
A 2026 review identifies multiple forms of programmed cell death as contributors to aortic dissection progression but finds limited clinical ...
ARDS subphenotypes offer a path toward personalized critical care
A review finds that ARDS can be separated into hyperinflammatory and hypoinflammatory profiles, while also showing why combining blood biomarkers ...
LPA₃ signaling and biological functions: from physiological regulation to disease-targeted therapy
A 2026 review summarizes LPA₃ signaling across tissues and diseases, identifies possible therapeutic applications, and frames selective antagonists, biased ligands ...
Review assesses CCT6A as a disease biomarker and therapeutic target
A 2026 review presents CCT6A as a candidate diagnostic and prognostic biomarker in cancer while highlighting context-dependent mechanisms, absent subunit-specific ...
Sepsis Treatments Shift Toward Precision, Multi-System Pharmacology
An editorial reviewing 21 contributions argues that sepsis therapy is shifting from broad cytokine suppression toward phenotype- and timing-based treatments ...
Narrative Review: Multi-Omics Has Not Validated Anti-Obesity Drug Selection
A narrative review finds that multi-omics has not yet produced a validated test for selecting anti-obesity medication in people with ...
AI could clarify molecular diversity in ovarian cancer liver metastases
A Mini Review finds that AI-assisted integration of genomic and spatial data may reveal lesion-specific biology in ovarian cancer liver ...
Genetic map of osteogenesis imperfecta guides precision care
A review finds that genetically distinct forms of osteogenesis imperfecta require molecular diagnosis, subtype-aware treatment and combined orthopedic, medical and ...
Singapore’s A*STAR and HistoIndex Join Forces to Speed Fibrosis Drug Development
Singapore's A*STAR has signed a Memorandum of Understanding with AI digital pathology firm HistoIndex to quantitatively evaluate preclinical therapeutic candidates ...
Stress Hormone Receptor Emerges as Shared Master Switch Behind Chronic Inflammation
A new Frontiers in Pharmacology perspective argues that dysregulated glucocorticoid receptor signaling is a shared upstream driver of chronic inflammation ...
Deep Learning Meets Its Match in Genetic Disease Prediction as Uncertainty Steals the Show
A deep neural network lost the accuracy race against random forest and SVM on a genetic disease benchmark, but its ...
Japan’s National Center Biobank Network Tops 250,000 Participants and 800,000 Biospecimens
A new review details how Japan's National Center Biobank Network has grown past 250,000 participants and 800,000 biospecimens, fueling discoveries ...
Personalized Cancer Spheroids Bring Tumor Reality Into the Lab
A new review highlights how patient-derived 3D cancer spheroids could transform precision oncology by recreating tumor architecture, drug resistance, and ...
EGFR Co-Targeting with Nanocarriers Offers New Precision Path for Triple-Negative Breast Cancer
A new review in Genes & Diseases outlines how co-targeting EGFR alongside other tumor-driving molecules, delivered via nanocarriers, could enable ...
Skin Biopsy Outperforms Invasive Surgery in Global Mitochondrial Disease Study
An international study shows that functional testing on cells grown from a small skin biopsy can diagnose mitochondrial disease, often ...
Weill Cornell Medicine Lands Fall Grants to Attack Hard-to-Treat Cancers
New awards from the AACR, Department of Defense and National Cancer Institute will fund enhancer hub research, ovarian cancer immunotherapy, ...
Leukemia That Refuses to Choose: The Science of Mixed Phenotype Acute Leukemia
A new review in Cancer Cell International synthesizes contemporary classification, clonal biology, and precision therapy for mixed phenotype acute leukemia, ...
