Oral Microbiome, Metabolites and Immune Signals Linked in Recurrent Mouth Ulcers
A small integrated study found that recurrent aphthous ulceration is associated with coordinated shifts in oral bacteria, serum metabolites and ...
Tag: oxidative stress
Plant Compounds Show Promise Against Pesticide-Linked Sperm Damage in Animal Studies
A systematic review of 33 animal studies finds that antioxidant-rich natural products such as sage, curcumin and quercetin counteract many ...
Probiotics, Prebiotics and Synbiotics Show Broad Metabolic and Hormonal Benefits in PCOS Meta-Analysis
A meta-analysis of twenty randomized controlled trials and an umbrella review of eleven meta-analyses finds that prebiotics, probiotics, and synbiotics ...
Fermented Potato Peel Extract Eased Fatty Liver Disease in Obese Rats
A study in obese rats found that potato peel extract fermented with Rhizopus oryzae reduced hepatic fat accumulation, improved lipid ...
Quercetin Plus Low-Dose Gamma Rays Curbed Chemically Induced Liver Cancer in Rats
In a rat model of chemically induced liver cancer, combining oral quercetin with fractionated low-dose gamma irradiation outperformed either treatment ...
Swim Exercise and Scent Leaf Extract Reverse Cardiometabolic Changes in Obese Rats
A 22-week rat study found that swimming exercise and Ocimum gratissimum leaf extract, alone or combined, significantly reversed obesity, high ...
Half of Children with Immune Thrombocytopenia Show Zinc Deficiency, Study Finds
A cross-sectional study of 74 Egyptian children and adolescents with primary immune thrombocytopenia found zinc deficiency in half of patients ...
Plant Phenolic Compounds Show Promise Against Disease, but Human Evidence Lags
A new review in Discover Molecules synthesizes the chemistry, limited bioavailability, and gut-brain interactions of plant phenolic compounds, cautioning that ...
Stroke begins years earlier: vascular dysfunction offers a window for prevention
A new review argues that stroke is the endpoint of progressive vascular failure and that translational models can uncover biomarkers ...
Antioxidant Supplement Blunts Radiation-Linked DNA Repair Signals in Interventional Physicians
A pilot clinical study found that a single morning dose of a multi-ingredient oral antioxidant formulation significantly attenuated acute DNA ...
Bacteria’s Antioxidant Defenses Mapped in Systematic Review of 27 Studies
A systematic review of 27 studies maps how Gram-positive and Gram-negative bacteria use enzymes, thiols, metal homeostasis, and biofilm matrices ...
Ellagic Acid Eases Paraquat-Induced Oxidative Stress in Piglet Muscle
A piglet study found that dietary ellagic acid improved antioxidant status and altered amino acid and fatty acid metabolism in ...
Systematic Review Maps How Honey Compounds Might Complement Liver Cancer Therapy
A systematic review of preclinical studies suggests honey and its flavonoids show anti-hepatocellular carcinoma mechanisms, though no rigorous human trials ...
Oxidative stress scavenger 2-HOBA proves safe but shows no significant benefit in rheumatoid arthritis trial
A randomized phase 2 trial found 2-HOBA was safe and well tolerated in rheumatoid arthritis patients but did not significantly ...
TBHQ Shows Protective Effects Against Cisplatin-Induced Neurotoxicity in Rats
A rat study found that the antioxidant compound TBHQ reduced cisplatin-induced cognitive deficits, oxidative stress and hippocampal inflammation.
Traditional Chinese Medicine Formula Kangxianling Shows Anti-Fibrosis Effects in Rats by Suppressing Ferroptosis
A preclinical study reports that Kangxianling Decoction reduced renal fibrosis in a rat model by suppressing ferroptosis through the p53/GPX4 ...
Three Oxidative Stress Genes Emerged as Key Players in Kidney Reperfusion Injury
A combined bioinformatic and experimental study identified FOS, FOSB and GDF15 as oxidative stress-related genes upregulated in renal ischemia-reperfusion injury ...
Artesunate Shows Promise Against Rheumatoid Arthritis by Triggering Ferroptosis in Synovial Cells
A new preclinical study reports that artesunate suppresses activated synovial fibroblasts and eases collagen-induced arthritis in mice by inducing ferroptosis ...
PIK3CA mutation rewires immune and metabolic networks in cervical cancer cells
CRISPR-engineered cervical cancer cells carrying the PIK3CA-E545K mutation show coordinated immune signaling and metabolic rewiring, driven by suppressed lipid biosynthesis ...
Cannabidiol shows preclinical promise against Alzheimer’s disease, but key evidence gaps remain
A new review finds cannabidiol consistently reduces neuroinflammation and oxidative stress in Alzheimer's preclinical models, but evidence for amyloid, tau, ...
