Oxidative Stress Gene Signature Flags Prostate Cancer Recurrence Risk
A LASSO-based risk score built from oxidative stress-related genes predicts biochemical recurrence in prostate cancer, with LAMP5 knockdown reducing PC3 ...
Tag: oxidative stress
Gasdermin D and E Play Distinct Roles in Photoreceptor Degeneration
A new review distinguishes a myeloid gasdermin D inflammatory relay from photoreceptor-intrinsic gasdermin E lysis in retinal degeneration and grades ...
Tea Plants Under Flood Stress: Hypoxia Signals and Metabolic Trade-offs Revealed
A new review synthesizes how hypoxia signaling and metabolic reprogramming shape tea's response to waterlogging, revealing a trade-off between flood ...
Black Phosphorus Shows Promise for Jaw Joint Arthritis, but Evidence Remains Early
A new review argues that black phosphorus biomaterials could address inflammation, oxidative stress, and bone remodeling in jaw joint osteoarthritis, ...
Fermented Soybean Peptides Show Antioxidant Effects in Immunosuppressed Mice
Researchers purified ten antioxidant peptides from Tongchuan Douchi and showed that the fraction raised antioxidant enzyme activity and lowered lipid ...
Ferulic Acid Niosomes Shield Rat Testes from Chemotherapy Damage in Preclinical Study
A rat study found that ferulic acid loaded into niosomes outperformed the free compound in reducing doxorubicin-induced testicular damage across ...
LncRNA SBF2-AS1 Worsens Heart Injury After Attack via miR-149-5p/PHLPP2 Axis
New research identifies the SBF2-AS1/miR-149-5p/PHLPP2 axis as a driver of cardiomyocyte injury after acute myocardial infarction in mouse and cell ...
Astaxanthin Shows Anti-Cancer Activity in Breast Cancer Models, Review Finds
A narrative review consolidates preclinical evidence that the carotenoid astaxanthin inhibits breast cancer cell proliferation, metastasis and angiogenesis, while stressing ...
CaMKII Emerges as Central Molecular Hub Driving the Ageing Heart
A new review synthesizes preclinical evidence that the CaMKIIδ kinase integrates calcium dysregulation, inflammation, autophagy failure, mitochondrial decline and DNA ...
Sesame Oil and Alpha-Lipoic Acid Shield Rat Testes from Heat Damage
A rat study found that combining sesame seed oil with alpha-lipoic acid largely reversed testicular damage, sperm defects, and fertility ...
Synbiotic Supplements Show Mixed Effects on Oxidative Stress Markers, Meta-Analysis Finds
An updated meta-analysis of 18 randomized controlled trials finds synbiotic supplementation associated with favorable shifts in several oxidative stress biomarkers, ...
Boiled and Finely Ground Balsam Apple Leaf Powder Lowers Cholesterol in Rats
A rat study found that cooking and sieving Momordica balsamina leaf powder into fine fractions improved its extractable polyphenol content ...
Endometriosis Linked to Trace Element Imbalance and Oxidative Stress in New Study
A case-control study of 120 women in India found that endometriosis was associated with elevated arsenic, lead, mercury, copper, and ...
Common Nanomaterials Show Mutagenic Potential in Mouse Lung Cell Assay
A new in vitro study finds that mesoporous silica and graphene oxide both reduce cell viability and significantly increase mutations ...
Curcumin and Pentoxifylline Show Modest Kidney Benefits in Six-Month CKD Trial
An open-label randomized trial in Egypt found that six months of adjunctive curcumin or pentoxifylline in stage 3–5 chronic kidney ...
Chitosan Nanoparticles in GelMA Hydrogel Deliver Resveratrol in pH-Responsive Manner In Vitro
An in vitro study reports a chitosan nanoparticle and GelMA hydrogel platform that releases resveratrol faster at acidic pH and ...
Bile Acid TUDCA Shows Liver Protection Across Diseases, But Human Evidence Remains Thin
A new narrative review maps how the bile acid TUDCA relieves ER stress, inflammation, oxidative damage, and apoptosis in liver ...
Cellular Stress Protein JWA Emerges as Context-Dependent Redox Hub in Aging and Disease
A new narrative review synthesizes how the multifunctional protein JWA intersects with redox homeostasis across cancer, neurodegeneration and tissue injury, ...
MicroRNA miR-15b-5p linked to severe pneumonia severity and epithelial cell injury
A study of 140 pneumonia patients and 65 healthy controls found that elevated serum miR-15b-5p distinguished severe from mild pneumonia, ...
Berberine shows promise against type 2 diabetes, but clinical proof is still lacking
A new narrative review finds berberine may influence multiple pathways in type 2 diabetes, but most evidence remains preclinical and ...
