Lymphoid Structures in Lung Inflammation Predict Survival After Therapy
A study of 254 lung cancer patients found that tertiary lymphoid structures in peritumoral inflammation are more mature and prognostically ...
Tag: NSCLC
T-DXd Plus Osimertinib Shows Benefit in HER2-Overexpressing Resistant Lung Cancer
A multicenter real-world study has reported that combining trastuzumab deruxtecan with osimertinib may offer clinical benefit for patients with HER2-overexpressing ...
When Lung Cancer Shrinks but Surgery Turns Dangerous: One Case’s Warning
A single case report shows that pathologic complete response after neoadjuvant chemoimmunotherapy did not restore a safe dissection plane in ...
JEEPERS Corrects Hidden Methylation Errors in Cell-Free DNA Sequencing
A new computational framework called JEEPERS detects and corrects methylation errors caused by jagged ends in cell-free DNA, improving cancer ...
Four Radiomic Texture Features Survive the Leap from Clinical CT to Micro-CT in Lung Cancer
A study of 60 NSCLC patients finds that only four texture-based radiomic features remain reproducible across clinical CT, ex vivo ...
EGF-depleting vaccine plus nivolumab shows survival signal in advanced NSCLC
A phase II trial reports 11.9-month median overall survival with CIMAvax-EGF plus nivolumab in previously treated advanced NSCLC, with the ...
Droplet Microfluidics Yields Uniform Core-Shell Microspheres for 3D NSCLC Models
A droplet microfluidic platform produces uniform HAMA/Matrigel core-shell microspheres of about 450 micrometers for in vitro NSCLC tumor modeling.
Enzyme PLA2G4A fuels lung cancer growth through an HSF1 signaling axis
A new study reports that the enzyme PLA2G4A promotes non-small cell lung cancer proliferation, survival and metastasis through an SP1–IL-1β–MAPK–HSF1 ...
Stress and cancer immunotherapy: distress linked to poorer checkpoint inhibitor outcomes
A new review finds that pretreatment psychological distress is consistently associated with poorer outcomes after immune checkpoint inhibitor therapy, while ...
Cell stress sensors ATF4 and ATF6 steer how lung cancer cells cope with glucose starvation
A new study shows that the stress sensors ATF4 and ATF6 coordinate transcriptional and metabolic responses to glucose deprivation in ...
Attention-driven multimodal AI shows promise for lung cancer diagnosis, review finds
A systematic review of 43 studies finds that attention-based multimodal deep learning consistently outperforms single-modality approaches across lung cancer diagnostic ...
Class III BRAF alterations linked to shorter survival in metastatic NSCLC
A retrospective multicenter study linked class III BRAF alterations in metastatic NSCLC to shorter overall survival and distinct co-mutation patterns ...
Zidesamtinib shows 94% response rate in TKI-naive advanced ROS1-positive lung cancer
New results from the global Phase I/II ARROS-1 trial indicate clinically meaningful activity with the investigational drug zidesamtinib in patients ...
Retrospective Chinese NSCLC study links compound EGFR mutations to poorer TKI response
A retrospective single-center analysis of 452 Chinese patients with non-small cell lung cancer associated compound and co-occurring EGFR mutations with ...
Review maps NSCLC-to-SCLC transformation amid expanding lung cancer treatments
A 2026 literature review synthesizes clinical, diagnostic, molecular and therapeutic evidence on transformation from non–small cell lung cancer to small ...
Post-treatment serum IL-6 independently associated with progression in observational cohort of advanced NSCLC with COPD
In a two-center observational cohort of 120 patients with advanced NSCLC and COPD, higher serum IL-6 measured after six treatment ...
Massive Turkish Genome Study Maps Hidden Mutation Patterns in Advanced Lung Cancer
A 1,500-patient next-generation sequencing study from Gazi University reveals EGFR and KRAS as dominant drivers in advanced NSCLC, with distinct ...
Iran’s National Lung Cancer Guideline Fails Key Quality Tests, AGREE II Appraisal Reveals
A structured AGREE II appraisal of Iran's 2018 national NSCLC guideline found strong clarity of presentation but major weaknesses in ...
Add-On Homeopathy Linked to Better Quality of Life and Longer Survival in Advanced Lung Cancer Trial
A controversial clinical trial has once again thrust homeopathy into the center of a scientific firestorm. In a prospective, randomized, ...
How Nutrient Availability Rewires Mitochondria and Cytoskeleton in 3D Lung Cancer Models
A new systems-level study in 3D lung adenocarcinoma models shows that nutrient availability drives tumour cells into two distinct mitochondrial ...
POPULAR NEWS
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CRISPR Beta-Cell Regeneration Shows Early Promise for Long-Term Diabetes Management
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Sudan Study Reveals Gaps in Kidney Stone Prevention Care
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Machine Learning Model Predicts Pediatric Sepsis Risk Using Routine Clinical Indicators
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ChatMPC Integrates Natural Language Processing with Predictive Control for Autonomous Driving