Local hyperthermia at 41 °C alleviates imiquimod-induced psoriasiform inflammation by activating an HSF1–METTL14–m6A–CRYAB regulatory axis that suppresses NF-κB signaling.
A scientific review in Molecular Biology Reports analyzes four key pathways linking PINK1-Parkin mitophagy to sepsis pathogenesis and surveys prospective ...
Targeted sequencing of 28 stage IE gastric MALT lymphoma cases found a shared low mutational burden across H. pylori-positive and ...
Endosialin-positive fibroblasts and pericytes drive colorectal cancer angiogenesis through NF-κB and HIF-1α signaling that boosts VEGFA secretion, and an anti-endosialin ...
A new Cell Division study reports that linalool stabilizes the NR3C2 protein in gastric cancer cells, activating NFKBIZ and suppressing ...
A new study reports that the cytokine IL-17A drives malignant T-cell proliferation in cutaneous T-cell lymphoma by increasing mitochondrial electron ...
An in-vitro study found that Xanthium strumarium extract reduced selected inflammatory signals and increased hyaluronan production in TNF-α/IFN-γ-stimulated HaCaT keratinocytes.
A review finds that protein modifications regulate immune inflammation and epithelial barrier dysfunction in ulcerative colitis through mechanisms that remain ...
A controlled study in male rats found that quercetin reduced many metabolic, reproductive, oxidative, and inflammatory changes associated with formaldehyde ...
A review finds that engineered delivery can improve herbal-based diabetic wound treatments, but direct evidence linking local exposure, NF-κB activation ...
A preclinical cell-and-mouse study found that Bruceine D inhibited osteoclast formation through effects involving STAT3, NF-κB and NFATc1 while improving ...
Researchers developed a near-infrared-responsive microneedle patch that delivers cryptochlorogenic acid via ZIF-8 nanoparticles to inhibit MMP3, MMP9 and MMP13 and ...
A new review reveals how the tumor suppressor and deubiquitinating enzyme CYLD is switched on and off by phosphorylation, ubiquitination, ...
The first genome-wide methylation map of the FXTAS brain reveals epigenetic changes in immune, oxidative stress, and myelination genes that ...
A new method called CCI-seq captures large-scale cell–cell interaction networks in tissues while preserving full single-cell transcriptomes, revealing interaction-driven gene ...
A new review in Annals of Hematology details how molecular profiling and a growing arsenal of targeted and immune-based therapies ...
In the intricate web of immune system regulation, the balance between effective defense and damaging inflammation is critically maintained through ...
