Early Gastric Carcinoma with Lymphoid Stroma Shows Lower Metastasis and Higher Survival
A multicenter study reveals that early gastric carcinoma with lymphoid stroma carries a significantly lower rate of lymph node metastasis ...
Tag: lymph node metastasis
Gastric Cancer Metastasis Patterns Reveal Distinct Molecular Targets
A new review in Annals of Gastroenterological Surgery proposes treating gastric cancer metastasis as distinct patterns, identifying route-specific biomarkers and ...
Gut Metabolite Indole-3-Propionic Acid Promotes Lymph Node Metastasis in Gastric Cancer
Researchers found that gut microbiota-derived indole-3-propionic acid accelerates gastric cancer lymph node metastasis by stimulating lymphatic endothelial cell remodeling through ...
Study Evaluates Papillary Thyroid Carcinoma Subtypes Under WHO 2022 Framework
A retrospective analysis of 173 papillary thyroid carcinoma cases reclassified under the WHO 2022 framework found that lymphatic invasion and ...
MRI habitat radiomics maps tumor diversity to predict lymph node spread in early-stage cervical cancer
A four-habitat MRI radiomics model combined with clinical variables predicted lymph node metastasis in early-stage cervical cancer with a test ...
Research report: Esophageal adenosquamous carcinoma with mucinous carcinoma-predominant lymph node metastases: a case report
A rare case report describes an esophageal adenosquamous carcinoma in which lymph node metastases were overwhelmingly composed of mucinous carcinoma, ...
Lymph-Node Radiomics Outperforms Tumor-Based CT Analysis for Predicting Colorectal Cancer Spread
A single-center proof-of-concept study found that CT-based multi-station lymph-node radiomics significantly outperformed primary-tumor radiomics for preoperative prediction of lymph node ...
Circular RNAs linked to poorer survival in cholangiocarcinoma, meta-analysis finds
A meta-analysis of 46 studies finds that high expression of oncogenic circular RNAs is associated with poorer overall survival in ...
AI Framework Combines Imaging, Genomics and Spectral Data for Oral Cancer Research
A retrospective deep learning prototype called XceptionAttnV1 processes multiple data types for oral cavity squamous cell carcinoma but has not ...
CT-based habitat radiomics flags heavy nodal spread in thyroid cancer, with caveats
A retrospective two-centre study found that a habitat radiomic model based on contrast-enhanced CT distinguished heavy from light central nodal ...
Seven-case study maps the morphology of ETV6::NTRK3-fused thyroid cancer
A seven-case study details the histological and cytopathological features of papillary thyroid carcinoma carrying the ETV6::NTRK3 gene fusion.
Core Needle Biopsy Falls Short for HER2-Low Breast Cancer Classification, Study Finds
A retrospective study of 1,919 breast cancer patients in China found core needle biopsy reliably determines binary HER2 status but ...
Keratin 18 linked to aggressive head and neck cancer and lymph node spread
A study in Cellular Oncology reports that keratin 18 is upregulated in aggressive head and neck squamous cell carcinoma and ...
Tumor cell program tied to lymphatic responses in aggressive thyroid cancer
A multi-omics study links an extracellular matrix-associated epithelial state and a SERPINA1–SOX4–FN1 molecular axis to lymphatic endothelial responses in papillary ...
Retrospective analysis finds uncertain HER2-low survival link in esophagogastric junction adenocarcinoma
A retrospective study of 74 resected esophagogastric junction adenocarcinomas found longer overall survival in HER2-low tumors, but HER2-low status was ...
Advanced Diffusion MRI Combined With Clinical Factors Shows Promise for Predicting Lymph Node Spread in Endometrial Cancer
A prospective study of 73 patients found that whole-tumor histogram features from five non-Gaussian diffusion MRI models, particularly DKI kurtosis ...
AI Reads Preoperative Endoscopic Biopsies to Gauge Lymph Node Spread in Early Gastric Cancer
A multimodal transformer-based AI framework achieved an AUC of 0.727 on preoperative endoscopic biopsy slides for predicting lymph node metastasis ...
Bethesda thyroid categories associated with tumor aggression in single-center study
A retrospective study of 8,595 thyroid fine-needle aspirations found that higher Bethesda categories were associated with aggressive surgical pathology, particular ...
IL1RAP associated with aggressive features in papillary thyroid carcinoma
IL1RAP was associated with aggressive features in papillary thyroid carcinoma, while cell experiments linked its expression to proliferation, invasion, EMT-like ...
Silenced Thyroid Gene CRABP1 Signals Aggressive Cancer Cells, Study Finds
A single-cell and epigenetic study links loss of the retinoid-binding protein CRABP1 to an invasive malignant epithelial cell state in ...
